Title
Hyrtinadines C and D, New Azepinoindole-Type Alkaloids from a Marine Sponge Hyrtios sp.
Author
Takaaki Kubota, Kenta Nakamura, Kanae Sakai, Jane Fromont, Tohru Gonoi, Jun’ichi Kobayashi
Year
2016
Journal
Chemical and Pharmaceutical Bulletin
Abstract
New bisindole alkaloids, hyrtinadines C (1) and D (2), have been isolated from an Okinawan marine sponge Hyrtios sp. The structures of hyrtinadines C (1) and D (2) were elucidated based on analyses of the spectral data. Hyrtinadines C (1) and D (2) were the relatively rare alkaloids possessing a 3,4-fused azepinoindole skeleton. Hyrtinadines C (1) and D (2) showed antimicrobial activity
Instrument
J-600
Keywords
Circular dichroism, Absolute configuration, Pharmaceutical