Title
New picrotoxane terpenoids, austrobuxusin A-D, from the Australian endemic plant Austrobuxus swanii
Author
Ozlem Demirkiran, Marc Campitelli, Chao Wang, Yunjiang Feng
Year
2016
Journal
Tetrahedron
Abstract
Four new picrotoxane terpenoids, austrobuxusin A–D (1–4), were isolated from the Australian endemic plant Austrobuxus swanii. Their structures were fully characterized by 1D- and 2D-NMR and MS data. The relative configurations of compounds (1–4) were assigned by phase-sensitive ROESY experiment. The absolute configuration of austrobuxusin A (1) was determined by the comparison of experimental and DFT-calculated CD spectra. This is the first report of picrotoxane terpenoids from the Australian plant Austrobuxus swanii.
Instrument
J-715
Keywords
Circular dichroism, Absolute configuration, Natural products, Pharmaceutical