Title
Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activitieslammatory activitiesretain–>
Author
Yanan Yang, Yawen An, Wei Wang, Ning Du, Jinghua Zhang, Ziming Feng, Jianshuang Jiang, Peicheng Zhang
Year
2017
Journal
Acta Pharmaceutica Sinica B
Abstract
Two new compounds, named lyciumlignan D (1) and lyciumphenyl propanoid A (2), along with seven known compounds, were isolated from the root bark of Lycium chinense. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds 3single bond9 were isolated from this genus for the first time. In the in vitro assay, compounds 3, 6, and 7 exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L.
Instrument
J-815
Keywords
Circular dichroism, Stereochemistry, Natural products, Pharmaceutical