Title
Optical Modulation of Azobenzene-Modified Peptide for Gold Surface Binding
Author
Joseph M. Slocik, Zhifeng Kuang, Marc R. Knecht, Rajesh R. Naik
Year
2016
Journal
A European Journal of Chemical Physics and Physical Chemisty
Abstract
The ability to precisely and remotely modulate reversible binding interactions between biomolecules and abiotic surfaces is appealing for many applications. To achieve this level of control, an azobenzene-based optical switch is added to nanoparticle-binding peptides in order to switch peptide conformation and attenuate binding affinity to gold surfaces via binding and dissociation of peptides.
Instrument
J-815
Keywords
Circular dichroism, Secondary structure, Ligand binding, Nanostructures, Materials, Biochemistry