Title
pH-Responsive Fluorescence Change Based on Dynamic Exchange between Emitting Aggregate and Quenching Monomer in Donor-Acceptor Dyes bearing Carboxylic Groups
Author
Tsutomu Ishi-I, Taishi Nakanishi
Year
2018
Journal
European Journal of Organic Chemistry
Abstract
pH imaging and measurement in biological systems is important because changes in pH are closely related with physiological and pathological processes. In this paper, we report a pH-responsive fluorescence change based on the dynamic exchange between emitting aggregate state and quenching monomer state. At low pH, the aggregate bearing a neutral carboxylic acid group in its protonated form continues to emit red light. In contrast, at high pH, the aggregate dissociates to the fluorescence quenching monomer due to electrostatic repulsion among the anionic carboxylate moieties generated from the deprotonation process, resulting in a pH-responsive change.
Instrument
FP-8600
Keywords
Fluorescence, Quantum yield, Chemical stability, Materials