Phenolic constituents from the roots of Alangium chinense

By Yan Zhang, Yun-Bao Liu, Yong Li, Shuang-Gang Ma, Li Li, Jing Qu, Dan Zhang, Jian-Dong Jiang, Shi-Shan Yu

July 28, 2017

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  • Technique

  • Industry

Title

Phenolic constituents from the roots of Alangium chinense

Author

Yan Zhang, Yun-Bao Liu, Yong Li, Shuang-Gang Ma, Li Li, Jing Qu, Dan Zhang, Jian-Dong Jiang, Shi-Shan Yu

Year

2016

Journal

Chinese Chemical Letters

Abstract

Three new phenolics (1–3) and twenty-eight known compounds (4–31) were isolated from an ethanolic extract of roots of Alangium chinense. Compound 11 exhibited antiviral activity against Coxsackie virus B3 with IC50 values of 16.89 μmol/L. Compounds 1,10–17, 19–21, and 23 showed strong antioxidant activity against Fe2+-cysteine-induced rat liver microsomal lipid peroxidation, with IC50 values of 0.14–8.18 μmol/L.

Full Article

http://www.sciencedirect.com/science/article/pii/S1001841716301231

Instrument

J-815

Keywords

Circular dichroism, Absolute configuration, Medicinal