We studied the impact of achiral substituents on the chiral supramolecular architectures of diketopyrrolo[3,4-c]pyrrole–1,2,3-1H-triazole (DPP) dyes. We decorated the same… Continue reading Chiral Diketopyrrolo[3,4-c]Pyrrole–1,2,3-1H-Triazole Dyes with Highly Tunable Properties in Solution and Thin Films
Carlos Morillo
April 4, 2023
Engineered living materials (ELMs) combine living cells with polymeric matrices to yield unique materials with programmable functions. While the cellular… Continue reading Additive Manufacturing of Engineered Living Materials with Bio-Augmented Mechanical Properties and Resistance to Degradation
Carlos Morillo
April 4, 2023
DJ-1 is a homodimeric protein that is centrally involved in various human diseases including Parkinson disease (PD). DJ-1 protects against… Continue reading The Reversible Low-Temperature Instability of Human DJ-1 Oxidative States
Carlos Morillo
April 4, 2023
Bacterial fibrillar adhesins are specialized extracellular polypeptides that promote the attachment of bacteria to the surfaces of other cells or… Continue reading Domain Shuffling of a Highly Mutable Ligand-Binding Fold Drives Adhesin Generation across the Bacterial Kingdom
Carlos Morillo
April 4, 2023
Marine elasmobranch fish contain urea, a protein denaturant, in their bodies. The urea-trimethylamine N-oxide (TMAO) counteraction mechanism contributes to urea-resistibility,… Continue reading Myosin Light Chain of Shark Fast Skeletal Muscle Exhibits Intrinsic Urea-Resistibility
Carlos Morillo
April 4, 2023
Chirality is a geometrical property described by continuous mathematical functions1–5. However, in chemical disciplines, chirality is often treated as a… Continue reading Photonically Active Bowtie Nanoassemblies with Chirality Continuum
Carlos Morillo
April 4, 2023
Receptor-derived peptides have played an important role in elucidating chemokine-receptor interactions. For the inflammatory chemokine CXCL8, a site II-mimetic peptide… Continue reading Effect of Macrocyclization and TAMRA-Labeling on Chemokine Binding Peptides
Carlos Morillo
March 16, 2023
Understanding and manipulation of catalytic enantioselectivity have emerged as a paramount challenge for decades. Inspired by nature, nanozymes with enantioselectivity… Continue reading Supramolecular Chiral Nanozymes with High and Switchable Enantioselectivity
Carlos Morillo
March 16, 2023
Crowding effects have a profound impact on the hierarchical organization of cellular architectures. In the fields of systems chemistry and… Continue reading Interplay of Depletion Forces and Biomolecular Recognition in the Hierarchical Assembly of Supramolecular Tubes
Carlos Morillo
March 16, 2023
Luminescent lanthanide complexes exhibiting chiroptical properties are attracting attention for their application in chiral optoelectronics and photonics, thanks to their… Continue reading Impact of Chiral Ligands on Photophysical and Electro-Optical Properties of β-Diketonate Europium Complexes in Circularly Polarized OLEDs
Carlos Morillo
March 16, 2023
Microbial communities respond to temperature with physiological adaptation and compositional turnover. Whether thermal selection of enzymes explains marine microbiome plasticity… Continue reading Enzyme Adaptation to Habitat Thermal Legacy Shapes the Thermal Plasticity of Marine Microbiomes
Carlos Morillo
March 16, 2023
Excessive macrophage activation induces the release of high levels of inflammatory mediators which not only amplify chronic inflammation and degenerative… Continue reading In Vitro and in Silico Studies of 7′′,8′′-Buddlenol D Anti-Inflammatory Lignans from Carallia Brachiata as P38 MAP Kinase Inhibitors
Carlos Morillo
March 16, 2023
Carlos Morillo
March 16, 2023
Membranes are important sites of intermolecular interactions in biological systems. However, they present significant analytical challenges as they contain multiple… Continue reading Couette Flow Fluorescence Detected Linear Dichroism for Analytes in Lipid Bilayers
Carlos Morillo
March 16, 2023
The main cause of non-typhoidal Salmonella (NTS) infection in humans is ingestion of contaminated animal-derived foods such as eggs, poultry… Continue reading A Novel Designed Membrane-Active Peptide for the Control of Foodborne Salmonella Enterica Serovar Typhimurium
Carlos Morillo
March 16, 2023
Carlos Morillo
March 16, 2023
Carlos Morillo
March 16, 2023
The misuse of antibiotics has led to the emergence of drug-resistant pathogens. Antimicrobial peptides (AMPs) may represent valuable alternative to… Continue reading The Impact of N-Glycosylation on the Properties of the Antimicrobial Peptide LL-III
Carlos Morillo
March 16, 2023
Continual progress in technologies that rely on water splitting are often hampered by the slow kinetics associated with the oxygen… Continue reading Chiral Electrocatalysts Eclipse Water Splitting Metrics through Spin Control
Carlos Morillo
March 16, 2023
Antimicrobial peptides (AMPs) possess bactericidal activity against a variety of pathogens depending on an overall balance of positively charged and… Continue reading Fine-Tuning the Antimicrobial Activity of β-Hairpin Peptides with Fluorinated Amino Acids
Carlos Morillo
March 16, 2023