2021 / Nature Communications
Furanosteroids, represented by wortmannin, viridin, and demethoxyviridin, are a special group of fungal-derived, highly oxygenated steroids featured by an extra …
2021 / Scientific Report
The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated …
Continue reading “Periplocin and cardiac glycosides suppress the unfolded protein response”
2021 / Nature Communications
A synthetic biology method based on heterologous biosynthesis coupled with genome mining is a promising approach for increasing the opportunities …
2021 / Journal of Asian Natural Products Research
Phytochemical investigation on the 80% EtOH extract of the whole plants of Zephyranthes grandiflora afforded three new 4a-epi-plicamine-type alkaloids, zephyranthines …
Continue reading “Cytotoxic plicamine alkaloids from the whole plants of Zephyranthes grandiflora”
2021 / Fitoterapia
Four new lignans, patulinones A−D (1–4) and three new acetophenone derivatives, patulinones E−G (5–7) were isolated from the leaves of …
2021 / Marine Drugs
Chemical investigation of secondary metabolites from the marine-derived fungus Aspergillus austroafricanus Y32-2 resulted in the isolation of two new prenylated …
2021 / Fitoterapia
Four new lignans, patulinones A−D (1–4) and three new acetophenone derivatives, patulinones E−G (5–7) were isolated from the leaves of …
2020 / Chinese Herbal Medicines Volume 12, Issue 3, July 2020, Pages 342-346
Objective To isolate the phenolic compounds obtained from the dried roots of Polygonum multiflorum and investigate their pharmacological activities. Methods …
Continue reading “New phenolic constituents obtained from Polygonum multiflorum”
2018 / Scientific Reports volume 8, Article number: 4433 (2018)
Over 12% of the world’s health resources are spent on treating diabetes, as high blood glucose is the third cause …
2020 / Scientific Reports volume 10, Article number: 13621 (2020)
Defects of vitamin B6 metabolism are responsible for severe neurological disorders, such as pyridoxamine 5′-phosphate oxidase deficiency (PNPOD; OMIM: 610090), …
2020 / Scientific Reports volume 10, Article number: 13721 (2020)
Colorectal cancer is the most common type of gastrointestinal cancers with poor survival and limited therapeutic options. In this study, …
2020 / Biointerface Research in Applied Chemistry, Research Articale Volume 10, Issue 5, 2020, 6550 - 6564
Syzygium cumini (L.) Skeels (or Eugenia jambolana) is a species that belongs to the Myrtaceae family been used empirically to …
