Three New Chalcones from the Aerial Parts of Angelica keiskei
Yun-Seo Kil, Jaeyoung Kwon, Dongho Lee, Eun Kyoung Seo
Helvetica Chimica Acta
Three new chalcones, 3′-carboxymethyl-4,2′-dihydroxy-4′-methoxychalcone (1), (±)-4,2′,4′-trihydroxy-3′-[(3-hydroxy-2,2-dimethyl-6-methylenecyclohexyl)methyl]chalcone (2), and 2′′-hydroxyangelichalcone (3), were isolated from the aerial parts of Angelica keiskei(Umbelliferae) together with five known compounds, artocarmitin A (4), (+)-cis-(3′R,4′R)-methylkhellactone (5), (−)-trans-(3′R,4′S)-methylkhellactone (6), 3,4-dihydroxanthotoxin (7), and (Z)-p-coumaryl alcohol (8). The known compounds 4 – 8 were identified fromA. keiskei for the first time. The structures of 1 – 3 were elucidated by interpreting spectroscopic data including 1D- and 2D-NMR.
Circular dichroism, Absolute configuration