Three new diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum W. T. Wang
Wen-Juan Xue, Bo Zhao, Jiang-Yu Zhao, Sh.Sh. Sagdullaev, Haji Akber Aisa
Three new diterpenoid alkaloids, designated naviconine (1), naviculine (2) and naviconitine (3), together with five known diterpenoid alkaloids (4)–(8) were isolated from the whole plant of Delphinium naviculare var. lasiocarpum W. T. Wang. The structures of the new compounds were established on the basis of spectroscopic analyses including HR-ESI-MS, 1D and 2D NMR analyses. All of the compounds were evaluated in vitro for cytotoxicity against HT-29, MDA-MB-231 and HeLa cancer cell lines using the MTT method.
Circular dichroism, Agriculture and environmental, Stereochemistry