Title
Two new diterpene alkaloids from the South China Sea Sponge Agelas aff. nemoechinata
Author
Tao Li, Bin Wang, Nicole J. de Voogd, Xu-Li Tang, Qi Wang, Mei-Jun Chu, Ping-Lin Li, Guo-Qiang Li
Year
2016
Journal
Chinese Chemical Letters
Abstract
Two new N-methyladenine-containing diterpenes, nemoechines F (1) and G (2), were isolated from the South China Sea sponge Agelas aff. nemoechinata. The structures were assigned on the basis of spectroscopic date. Compound 2 showed weak activity against Jurkat cell lines with IC50 of 17.1 μmol/L.
Instrument
J-810
Keywords
Circular dichroism, Stereochemistry, Medicinal