Title
Two new flavanone glycosides from Scutellaria galericulata with anti-inflammatory activities
Author
Kai Xiao, Qing-Tong Han, Lei Zhang, Sheng-Jun Dai
Year
2017
Journal
Phytochemistry Letters
Abstract
Two new flavanone glycosides, named scugalerosides A and B (1-2), were isolated from the whole plant of Scutellaria galericulata. Their chemical structures including absolute configurations were established on the basis of detailed physical data analyses. In vitro, two new compounds showed anti-inflammatory activities, with the inhibition rates of release of β-glucuronidase from polymorphonuclear leukocytes of rats being 43.7% and 45.1% at concentrations of 10 μM.
Instrument
J-815
Keywords
Circular dichroism, Stereochemistry, Natural products, Pharmaceutical