Title
Two new secondary metabolites from a fungus of the genus Robillarda
Author
Takeo Shimoyama, Mizuki Miyoshi, Tatsuo Nehira, Atsuko Motojima, Tsutomu Oikawa, Olivier Laurence, Yasuhiro Igarashi
Year
2018
Journal
The Journal of Antibiotics
Abstract
Two new compounds, robillafuran and (+)-robillapyrone, were isolated from the culture extract of a fungal strain of Robillarda along with (+)-monascuspyrone. The absolute configuration of (+)-robillapyrone and (+)-monascuspyrone was determined by ECD calculation. These three compounds showed preadipocyte differentiation activity at 10–40 μM.
Full Article
Instrument
J-720
Keywords
Circular dichroism, Absolute configuration, Natural products, Pharmaceutical