Title
Unusual crystal structure and chirality of uridine 5′-monophosphate coordination polymer
Author
Leilei Gu, Qi-ming Qiu, Pei Zhou, Liang Hao, Minghua Liu, Hui Li
Year
2017
Journal
RSC Advances
Abstract
Two types of Cu(II)–UMP-L coordination polymers, {[Cu2(UMP)2(bpda)2(H2O)3]·10H2O}n (1) and {[Cu2(UMP)2(bpe)2(H2O)2]·7H2O}n (2) (UMP = uridine 5′-monophosphate, bpda = 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene, bpe = 1,2-bis(4-pyridyl)ethylene), were designed and synthesized for researching the effect of auxiliary ligand. X-ray single-crystal diffraction analysis revealed that complex 1 is the first example of a 1D parallel double-bridged coordination polymer in a nucleotide–metal coordination complex, while complex 2 is a 2D grid coordination polymer. Based on their crystal structure analysis, their chirality, including molecular chirality, supramolecular helical chirality and auxiliary ligand's extended axial chirality (EAC), was studied by aqueous solution and solid state circular dichroism (CD) spectroscopy. The length and conjugated auxiliary ligand had an influence on the EAC.
Instrument
J-810
Keywords
Circular dichroism, Solid-state, DNA structure, Polymers, Ligand binding, Biochemistry