Found 9617 Results / Page 198 of 481
2018 / Scientific Reports
In majority of snakebite cases, the snake responsible for the bite remains unidentified. The traditional snakebite diagnostics method relies upon… Continue reading Rational truncation of aptamer for cross-species application to detect krait envenomation
2018 / ACS Applied Materials & Interfaces
Protein misfolding and abnormal self-assembly lead to the aggregates of oligomer, fibrils, or senior amyloid plaques, which is associated with… Continue reading Enhanced Photoresponsive Graphene oxide-modified g-C3N4 for Disassembly of Amyloid β Fibrils
2018 / Biomolecular NMR Assignments
BAF200 is a subunit of PBAF chromatin remodeling complex that contains an N-terminal AT-rich interaction domain (ARID). ARID domain in… Continue reading Sequential backbone resonance assignment of AT-rich interaction domain of human BAF200
2018 / Biologics
Cell surface protein, CD20, is extensively expressed on the surface of B cells. Antibodies targeting CD20 protein are being used… Continue reading Structural and functional comparability study of anti-CD20 monoclonal antibody with reference product
2018 / ACS Applied Materials & Interfaces
Enzymes are described as ideal green biocatalysts since they are highly specific and selective. However, their practical application is hampered… Continue reading Hairy Particles with Immobilized Enzymes: Impact of Particle Topology on the Catalytic Activity
2018 / Biochemical and Biophysical Research Communications
Mycoplasma pneumoniae forms an attachment organelle at one cell pole, binds to the host cell surface, and glides via a unique mechanism. A… Continue reading Production and characterization of recombinant P1 adhesin essential for adhesion, gliding, and antigenic variation in the human pathogenic bacterium, Mycoplasma pneumoniae
2018 / Molecular Pharmaceutics
The preparation of PLGA rods for sustained release applications via a hot-melt extrusion process employs heat and mechanical shear. Understanding… Continue reading Trehalose Limits Fragment Antibody Aggregation and Influences Charge Variant Formation in Spray-Dried Formulations at Elevated Temperatures
2018 / molecules
The formation of a guanine quadruplex DNA structure (G4) is known to repress the expression of certain cancer-related genes. Consequently,… Continue reading Design and Properties of Ligand-Conjugated Guanine Oligonucleotides for Recovery of Mutated G-Quadruplexes
2018 / Internationl Journal of Molecular Sciences
Because of their nutritional value, zinc oxide (ZnO) nanoparticles (NPs) are applied as a dietary source of zinc, by direct… Continue reading Protein Food Matrix–ZnO Nanoparticle Interactions Affect Protein Conformation, but May not Be Biological Responses
2018 / biomolecules
Prostate apoptosis response-4 (Par-4) is a 38 kDa largely intrinsically disordered tumor suppressor protein that functions in cancer cell apoptosis.… Continue reading pH-Induced Folding of the Caspase-Cleaved Par-4 Tumor Suppressor: Evidence of Structure Outside of the Coiled Coil Domain
2018 / analytical chemistry
The color expression of anthocyanin pigments in blue flowers is precisely controlled by the pigments’ chemical and physical environmental properties… Continue reading Imaging mass spectrometry analysis of flavonoids in blue viola petals and their enclosure effects on violanin during color expression
2019 / Journal of Functional Foods
The calcium-binding peptides were recognized as novel functional ingredients for improving calcium bioavailability. Pacific cod (Gadus Macrocephalus) bone gelatin hydrolysates… Continue reading Purification and characterization of a novel calcium-biding decapeptide from Pacific cod (Gadus Macrocephalus) bone: Molecular properties and calcium chelating modes
2018 / International Journal of Molecular Sciences
Activation of Wnt signaling induces Connexin43 (Cx43) expression via the transcriptional activity of β-catenin, and results in the enhanced accumulation… Continue reading Connexin43 Carboxyl-Terminal Domain Directly Interacts with p-Catenin
2019 / Bioorganic & Medicinal Chemistry
Daptomycin, a cyclic lipodepsipeptide antibiotic, has been used clinically since 2003 to treat serious infections caused by Gram-positive bacteria. Although 37 years have… Continue reading The effect of replacing the ester bond with an amide bond and of overall stereochemistry on the activity of daptomycin
2018 / molecules
Osmolytes are small organic compounds that can affect the stability of proteins in living cells. The mechanism of osmolytes’ protective… Continue reading Do Osmolytes Impact the Structure and Dynamics of Myoglobin?
2019 / European Journal of Pharmaceutics and Biopharmaceutics
In this communication, the effect of mannitol and trehalose crystallization on the unfolding of IgG1, a monoclonal antibody, in the frozen state with repeat freeze/thawunder different pH… Continue reading Freeze/thaw of IGG solutions
2018 / Plant Cell, Tissue, and Organ Culture (PTOC)
We have previously established that RiHSPRO2, a nematode resistance protein-like homolog from wild crucifer Rorippa indica (L.) Hiern is a potent candidate… Continue reading Rorippa indica HSPRO2 expression in transgenic Brassica juncea induces tolerance against mustard aphid Lipaphis erysimi
2018 / Nano Letters
The DNA origami technique has empowered a new paradigm in plasmonics for manipulating light and matter at the nanoscale. This… Continue reading Dynamic Plasmonic System That Responds to Thermal and Aptamer-Target Regulations
2018 / Chemistry of Natural Compounds
Danshen Injection (lyophilized powder) is an important clinical preparation with therapeutic effects for cardiovascular diseases in China. Phenolics are considered… Continue reading Two New Phenolics from Danshen Injection with Antioxidant Activity
2018 / Journal of Biological Chemistry
The histone variant CENP-ACse4 is a core component of the specialized nucleosome at the centromere in budding yeast and is required… Continue reading Conformational flexibility of histone variant CENP-ACse4 regulated by histone H4: a mechanism to stabilise soluble Cse4
