Multiple pyrenes as pendants of enantioimpure di‐/tripeptides (abbreviated as N‐LD‐C, N‐DL‐C, N‐LLD‐C and N‐DDL‐C) showed pyrene‐origin CPL and CD signals,… Continue reading Circularly polarised luminescence of pyrenyl di- and tri-peptides with mixed D- and L-amino acid residues
Leah Pandiscia, PhD
May 24, 2018
Sex-linked barring is a fascinating plumage pattern in chickens recently shown to be associated with two non-coding and two missense… Continue reading The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2A
Leah Pandiscia, PhD
July 28, 2017
Hydrogels are good candidates to satisfy many needs for functional and tunable biomaterials. How to precisely control the gel structure… Continue reading A glucose-sensitive block glycopolymer hydrogel based on dynamic boronic ester bonds for insulin delivery
Leah Pandiscia, PhD
July 28, 2017
The etiology of Parkinson’s disease (PD) relates to α-synuclein, a small protein with the ability to aggregate and form Lewy… Continue reading Interaction of α-synuclein with Rhus typhina tannin – Implication for Parkinson’s disease
Leah Pandiscia, PhD
July 28, 2017
Staphylococcus aureus is an opportunistic human pathogen able to transfer virulence genes to other cells through the mobilization of S. aureus pathogenicity islands… Continue reading Derepression of SaPIbov1 is independent of φNM1 type 2 dUTPase activity and is inhibited by dUTP and Dump
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Snake venoms contain various proteins, especially phospholipases A2 (PLA2s), which present potential applications in diverse areas of health and medicine. In… Continue reading BmajPLA2-II, a basic Lys49-phospholipase A2 homologue from Bothrops marajoensis snake venom with parasiticidal potential
Leah Pandiscia, PhD
July 28, 2017
The extent of heme extraction from myoglobin (Mb) by methylethyl ketone is found to be pH dependent and show three… Continue reading Three phases in pH dependent heme abstraction from myoglobin
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A new family of conjugates between a Zn(II)-tach complex and (indole)2 or benzofuran-indole amide minor groove binders connected through alkyl or… Continue reading Conjugates between minor groove binders and Zn(II)-tach complexes: Synthesis, characterization, and interaction with plasmid DNA
Leah Pandiscia, PhD
July 28, 2017
Three new sesquiterpene glycosides (1–3), three new glycerol glycosides (4–6), two new alkaloids (7–8), together with seven known compounds (9–15)… Continue reading Chemical constituents from the whole plants of Pilea cavaleriei Levl subsp. cavaleriei
Leah Pandiscia, PhD
July 28, 2017
Small interfering RNAs (siRNAs) present a strong therapeutic potential because of their ability to inhibit the expression of any desired… Continue reading PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo
Leah Pandiscia, PhD
July 28, 2017
We synthesized two mixed-ligand Cu(II) complexes containing different aroylhydrazone ligands and a pyridine co-ligand, namely, [Cu(L1)(Py)] (C1) and [Cu(L2)(Py)(Br)] (C2)… Continue reading Structure and biological properties of mixed-ligand Cu(II) Schiff base complexes as potential anticancer agents
Leah Pandiscia, PhD
July 28, 2017
Protein aggregation into oligomers and fibrils are associated with many human pathophysiologies. Compounds that modulate protein aggregation and interact with… Continue reading Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity
Leah Pandiscia, PhD
July 28, 2017
Acinetobacter radioresistens PR8 produces extracellular lipase depending upon growth media. In present work we not only screened the nutrient sources but… Continue reading Scale-up and inhibitory studies on productivity of lipase from Acinetobacter radioresistens PR8
Leah Pandiscia, PhD
July 28, 2017
EccA family proteins are conserved components of ESX secretion pathways in M. tuberculosis H37Rv. Here, we report the characterization of EccA3 (Rv0282),… Continue reading Characterization of EccA3, a CbbX family ATPase from the ESX-3 secretion pathway of M. tuberculosis
Leah Pandiscia, PhD
July 28, 2017
β-Glucuronidase from Aspergillus terreus Li-20 (AtGUS) can hydrolyze the glycyrrhizin (GL) into glycyrrhetinic acid 3-O-mono-β-D-glucuronide (GAMG) and glycyrrhetinic acid (GA). However, its… Continue reading Sequence Editing Strategy for Improving Performance of β-glucuronidase from Aspergillus terreus
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A method for obtaining fluorescence polarization data from an instrument designed to measure circular and linear dichroism is compared with… Continue reading Measuring fluorescence polarization with a dichrometer
Leah Pandiscia, PhD
July 28, 2017
The interaction of acetaminophen, a non-substrate anionic ligand, with Aldehyde Dehydrogenase was studied by fluorescence, UV-Vis absorption, and circular dichroism… Continue reading Interaction of Aldehyde dehydrogenase with Acetaminophen as examined by Spectroscopies and Molecular docking
Leah Pandiscia, PhD
July 28, 2017