Found 9617 Results / Page 147 of 481
2019 / Journal of Organometallic Chemistry
New types of polymers composed of bithiophene condensed with disilacyclohexadiene rings and benzothiadiazole were prepared by the platinum-catalyzed dehydrogenative bissilylation.… Continue reading Synthesis and optical properties of polymers with bithiophene condensed with disilacyclohexadiene rings and benzothiadiazole
2019 / Bioorganic Chemistry
In this study we describe the synthesis and characterisation of a new hydrazone-based fluorescent compound that is able to selectively… Continue reading A novel adaptive fluorescent probe for cell labelling
2019 / Bioorganic Chemistry
Novel water-soluble 4-aminonaphthalimides were synthesised and their cellular fluorescent imaging, cytotoxicity and ability to induced apoptosis evaluated. The lead compound 1 was… Continue reading Aminonaphthalimide hybrids of mitoxantrone and amonafide as anticancer and fluorescent cellular imaging agents
2019 / New Journal of Chemistry
Herein, we report the synthesis, molecular structures and bioevaluation of two different cationic copper(II) complexes with the third generation quinolone… Continue reading Copper(ii) complexes based on levofloxacin and 2N-donor ligands: synthesis, crystal structures and in vitro biological evaluation
2019 / Protein Expression and Purification
The protein ALL1 fused from chromosome 1q (AF1q) is overexpressed in a variety of cancers and acts to activate several… Continue reading Recombinant expression and purification of AF1q and its interaction with T-cell Factor 7
2019 / Analytical and Bioanalytical Chemistry
The i-motif is a biologically relevant non-canonical DNA structure formed by cytosine-rich sequences. Despite the importance of the factors affecting… Continue reading Assessing the influence of pH and cationic strength on i-motif DNA structure
2019 / Materials Letters
A fluorite-type compound, Pb0.35Bi0.65O1.59, was synthesized by a hydrothermal reaction. The crystal structure of the compound was refined using synchrotron… Continue reading Hydrothermal synthesis and crystal structure of a fluorite-type Pb0.35Bi0.65O1.59 compound with photocatalytic activity
2019 / International Journal of Pharmaceutics
Only few adjuvants are licensed for use in humans and there is a need to develop safe and improved vaccine… Continue reading One-pot synthesis and characterization of ovalbumin-conjugated gold nanoparticles: A comparative study of adjuvanticity against the physical mixture of ovalbumin and gold nanoparticles
2019 / Journal of the Science of Food and Agriculture
Peanut is among the most common of food allergies, and one of its allergens is Ara h 2. A previous… Continue reading Polyphenol‐oxidase‐catalyzed cross‐linking of Ara h 2: reaction sites and effect on structure and allergenicity
2019 / Inorganic Chemistry Frontiers
Chiral separation is of critical importance in many areas spanning from pharmaceutics and agriculture to catalysis. Coordination polymers and metal–organic… Continue reading Enantioselective separation under humid conditions by chiral Hofmann clathrates: new opportunities for vintage materials
2019 / Carbohydrate Research
As part of our ongoing investigation of the bioactive constituents from the roots of Glycyrrhiza uralensis Fisch., seven new flavonoid glycosides (1–7)… Continue reading Seven new flavonoid glycosides from the roots of Glycyrrhiza uralensis and their biological activities
2019 / Scientific Reports
Two new harziane diterpene lactones, possessing a 6/5/7/5-fused carbocyclic core containing a lactone ring system, harzianelactones A and B (1 and 2),… Continue reading Potent Phytotoxic Harziane Diterpenes from a Soft Coral-Derived Strain of the Fungus Trichoderma harzianum XS-20090075
2019 / Scientific Reports
Hearing and balance rely on the transduction of mechanical stimuli arising from sound waves or head movements into electrochemical signals.… Continue reading Nanomechanics of tip-link cadherins
2019 / Biochemistry
The G98R mutation in αA-crystallin is associated with the onset of presenile cataract and is characterized biochemically by an increased… Continue reading Functional Rescue of Cataract-Causing αA-G98R-Crystallin by Targeted Compensatory Suppressor Mutations in Human αA-Crystallin
2019 / Journal of Bacteriology
The prokaryotic βγ-crystallins are a large group of uncharacterized domains with Ca2+-binding motifs. We have observed that a vast number… Continue reading βγ-Crystallination Endows a Novel Bacterial Glycoside Hydrolase 64 with Ca2+-Dependent Activity Modulation
2019 / molecular pharmaceutics
In this work, two different approaches have been developed to predict the food effect and the bioequivalence of marketed itraconazole… Continue reading Prediction of Bioequivalence and Food Effect Using Flux- and Solubility-Based Methods
2019 / biomolecules
Studying drug–protein interactions has gained significant attention lately, and this is because the majority of drugs interact with proteins, thereby… Continue reading Unraveling Binding Mechanism of Alzheimer’s Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases
2019 / Molecular Biotechnology
Angiogenesis is a biological process finely tuned by a plethora of pro- and anti-angiogenic molecules, among which vascular endothelial growth… Continue reading Biochemical and Conformational Characterization of Recombinant VEGFR2 Domain 7
2020
Many pathogens take advantage of the dependence of the host on the interaction of hundreds of extracellular proteins with the… Continue reading The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding
2003 / Journal of Virology
Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus mouse… Continue reading The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex
