Found 9617 Results / Page 159 of 481
2019 / Biochimie
The interactions of 6–8 ring hairpin polyamides (PAs) with the minor groove of DNA have been investigated extensively. More recent… Continue reading DNA binding thermodynamics and site stoichiometry as a function of polyamide size
2019 / Journal of Natural Medicines
A new prenylated benzophenone, hypatulin C (1), was isolated from the leaves of Hypericum patulum together with a biogenetically related analog, hypelodin… Continue reading Prenylated benzophenone derivatives from Hypericum patulum
2019 / Marine Drugs
The outburst of microbial resistance to antibiotics creates the need for new sources of active compounds for the treatment of… Continue reading Identification of Antimicrobial Peptides from the Microalgae Tetraselmis suecica (Kylin) Butcher and Bactericidal Activity Improvement
2019 / Colloids and Surfaces B: Biointerfaces
In this study, we evaluated the adsorption of proteins to 2,2,6,6-tetramethylpiperidine-1-oxyl oxidized cellulose nanofibers (TOCNs) and their structures on the… Continue reading Structure retention of proteins interacting electrostatically with TEMPO-oxidized cellulose nanofiber surface
2019 / Polymer Journal
Polypeptides containing periodic aromatic residues in their main chains were synthesized via papain-catalyzed chemoenzymatic polymerization of tripeptide ester monomers under… Continue reading Periodic introduction of aromatic units in polypeptides via chemoenzymatic polymerization to yield specific secondary structures with high thermal stability
2019 / Crystal Growth & Design
Five derivatives of cyano-containing 9-alkyl-9H-aza[7]helicene were synthesized and their behavior in the crystallization was investigated. Only one of the derivatives,… Continue reading Effect of the Position of the Cyano Group on Molecular Recognition, Supramolecular Superhelix Architecture, and Spontaneous Resolution of Aza[7]helicenes
2019 / Biochemistry
The class D β-lactamase OXA-143 has been described as an efficient penicillinase, oxacillinase, and carbapenemase. The D224A variant, known as… Continue reading Importance of the β5−β6 Loop for the Structure, Catalytic Efficiency, and Stability of Carbapenem-Hydrolyzing Class D β-Lactamase Subfamily OXA-143
2019 / International Journal of Peptide Research and Therapeutics
Two new somatostatin analogs with a characteristic part of the sequence in their structures, -c(Cys-Phe-Trp-Lys-Thr-Cys)-, were synthesized and analyzed in… Continue reading The Analysis of the Structural Aspects of Cu (II) Binding by Cyclic His/Asp-Analogues of Somatostatin
2019 / Macromolecular Materials and Engineering
The Sonogashira–Hagihara coupling polymerization of ferrocene‐containing l‐phenylalanine‐derived optically active o‐, m‐, p‐substituted bis(iodophenylene) monomers 1o , 1m , 1p with 1,4‐diethynylbenzene (2) and 1,4‐diethynyl‐2,5‐bis[2‐(2‐methoxyethoxy)ethoxy]benzene (3) is carried out to obtain… Continue reading Synthesis, Chiroptical, and Redox Properties of Ferrocene‐Containing Optically Active Polymers
2019 / International Journal of Pharmaceutics
In this work, we implemented a supramolecular approach in order to combine photodynamic therapy (PDT) with gene therapy. We made… Continue reading Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes
2019 / Journal of Biological Chemistry
Thioredoxin (Trx) is a conserved, cytosolic reductase in all known organisms. The enzyme receives two electrons from NADPH via thioredoxin… Continue reading Functional analyses of ancestral thioredoxins provide insights into their evolutionary history
2019 / Molecular Immunology
The presence in cypress pollen of an important allergen, belonging to the gibberellin-regulated protein (GRP) family, has been suggested for… Continue reading Isolation of cypress gibberellin-regulated protein: Analysis of its structural features and IgE binding competition with homologous allergens
2019 / Carbohydrate Polymers
To address the need to biodegradable, electroactive conduits accelerating nerve regeneration, here we develop a nanocomposite hydrogel made of alginate… Continue reading An electroactive alginate hydrogel nanocomposite reinforced by functionalized graphite nanofilaments for neural tissue engineering
2019 / Biosensors and Bioelectronics
Nowadays, acquired immunodeficiency syndrome has become a formidable danger to human health, and its early diagnosis is urgent need with… Continue reading Beta-cyclodextrin-functionalized CdS nanorods as building modules for ultrasensitive photoelectrochemical bioassay of HIV DNA
2019 / ACS Sustainable Chemistry & Engineering
Metallized DNA is an exciting functional material having widespread utility toward multifunctional applications. However, conventional DNA metallization processes are time-consuming… Continue reading Facile Process for Metallizing DNA in a Multitasking Deep Eutectic Solvent for Ecofriendly C–C Coupling Reaction and Nitrobenzene Reduction
2019 / Food Hydrocolloids
Lysozyme (Ly), as an important natural preservative, easily interacts with anionic polysaccharides in food, which results in low and unstable… Continue reading Effect of carboxymethylcellulose on the affinity between lysozyme and liposome monolayers:evidence for its bacteriostatic mechanism
2019 / Dyes and Pigments
In this work, we designed and investigated two TADF molecules, AcCN and PxCN, introducing donor moieties into the 3,5-position of 4-pyridinecarbonitrile acceptor core.… Continue reading Molecular design of highly effective thermally activated delayed fluorescence emitters based on ortho-substituted donor-acceptor-donor pyridinecarbonitrile derivatives and their application for high-performance OLEDs
2019 / Bioorganic Chemistry
MicroRNAs are a ubiquitous class of non-coding RNAs able to regulate gene expression in diverse biological processes. Widespread miRNAs deregulation… Continue reading A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a
2019 / Journal of Functional Foods
Ovalbumin (OVA) is the major protein in egg white and has multiple functional properties. We prepared the covalent conjugate OVA–(−)-epigallo-catechin… Continue reading Function, digestibility and allergenicity assessment of ovalbumin–EGCG conjugates
2019 / ACS Applied Biomaterials
Photomedicine-based antimicrobial therapy has emerged as an alternative treatment for antibiotic-resistant microbial infections. Although various photosensitizers (PSs) have been reported… Continue reading Porphyrin Functionalized Gelatin Nanoparticle-Based Biodegradable Phototheranostics: Potential Tools for Antimicrobial Photodynamic Therapy
