Leah Pandiscia, PhD
October 11, 2018
Alangium longiflorum is currently in extinction crisis, which will likely severely hamper further phytochemical investigation of this plant species from new… Continue reading Antiproliferative Alkaloids from Alangium longiflorum, an Endangered Tropical Plant Species
Leah Pandiscia, PhD
October 11, 2018
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic α-helical region in the C-terminus,… Continue reading Antimicrobial and anti-inflammatory activities of chemokine CXCL14-derived antimicrobial peptide and its analogs
Leah Pandiscia, PhD
October 11, 2018
A hyphenated NMR technique (analytical HPLC with a DAD connected to MS, SPE, and NMR) has proven effective for the… Continue reading Minor Nortriterpenoids from the Twigs and Leaves of Rhododendron latoucheae
Leah Pandiscia, PhD
October 11, 2018
Bioactivity‐guided fractionation of the methanolic extract from the seeds of Euphorbia lathyris led to the isolation of eighteen lathyrane‐type diterpenoids including a… Continue reading Lathyrane‐type diterpenoids from the seeds of Euphorbia lathyrisL. with inhibitory effects on NO production in RAW 264.7 cells
Leah Pandiscia, PhD
October 11, 2018
Structure‐specific helicases, such as RecG, play an important role in the resolution of recombination intermediates. A bioinformatic analysis of mycobacterial… Continue reading RecGwed: A probable novel regulator in the resolution of branched DNA structures in mycobacteria
Leah Pandiscia, PhD
October 11, 2018
Three new 2-phenylnaphthalene derivatives, cherrevenaphthalenes A–C (1–3), and a new polyoxygenated cyclohexene derivative, (−)-uvaribonol F (4) together with six known… Continue reading 2-Phenylnaphthalenes and a polyoxygenated cyclohexene from the stem and root extracts of Uvaria cherrevensis(Annonaceae)
Leah Pandiscia, PhD
October 11, 2018
Gabapentin, an antiepileptic drug, is known to form stable helical structures in short peptides. Distinctly, we report on the newly… Continue reading Remarkable Modulation of Self-Assembly in Short γ-Peptides by Neighboring Ions and Orthogonal H-Bonding
Leah Pandiscia, PhD
October 11, 2018
Ustilaginoidins are a class of bis-naphtho-γ-pyrones, typically produced by Villosiclava virens, the pathogen of the rice false smut (RFS), which has… Continue reading New Ustilaginoidins from Rice False Smut Balls Caused by Villosiclava virens and Their Phytotoxic and Cytotoxic Activities
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
We demonstrate a new scheme for hydrogen peroxide (H2O2) detection through a distinctive fluorescence “on/off/on” mechanism. Specifically, we show that… Continue reading “On/off/on” hydrogen-peroxide sensor with hemoglobin-functionalized carbon dots
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Poly-γ-glutamic acid (PGA) was easily phosphorylated by direct addition of phosphorylating agents into the culture medium of Bacillus subtilis (natto). Tetrapolyphosphate salt… Continue reading Regulatory phosphorylation of poly-γ-glutamic acid with phosphate salts in the culture of Bacillus subtilis (natto)
Leah Pandiscia, PhD
October 11, 2018
Spatially confined environments are seen in biological systems and in the fields of biotechnology and nanotechnology. The confinement restricts the… Continue reading Thermal stability and conformation of DNA and proteins under the confined condition in the matrix of hydrogels
Leah Pandiscia, PhD
October 11, 2018
Removal of chondroitin sulfate glycosaminoglycan (GAG) chains with chondroitinase ABC I (chABC I) in CNS injury models promotes both saxon… Continue reading Establishment of Aromatic Pairs at the Surface of Chondroitinase ABC I: the Effect on Activity and Stability
Leah Pandiscia, PhD
October 11, 2018
FOXP2 is a transcription factor expressed in multiple tissues during embryonic development. FOXP2 regulates transcription by binding to DNA at… Continue reading A Phosphomimetic Study Implicates Ser557 in Regulation of FOXP2 DNA Binding
Leah Pandiscia, PhD
October 11, 2018
Acetoin is an important physiological metabolite excreted by microbes. Its functions include avoiding acidification, participating in regulation of the NAD+/NADH… Continue reading Structural and enzymatic characterization of acetolactate decarboxylase from Bacillus subtilis
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Photostability testing of therapeutic proteins is a critical requirement in the development of biologics. Upon exposure to light, pharmaceutical proteins… Continue reading Effects of photo-degradation on the structure, stability, aggregation, and function of an IgG1 monoclonal antibody
Leah Pandiscia, PhD
October 11, 2018