Found 9617 Results / Page 278 of 481
2014 / Neurobiology of Disease
Dementia with Lewy bodies (DLB), Parkinson’s disease (PD) and multiple system atrophy are characterized by the deposition of disease-associated α-synuclein. In the present… Continue reading Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread
2014 / Journal of Physical Chemistry B
The present study epitomizes the design, synthesis, photophysics, solvation, and interaction with calf-thymus DNA of a potential antitumor, anticancer quinoline-appended… Continue reading Design, Synthesis, Physicochemical Studies, Solvation, and DNA Damage of Quinoline-Appended Chalcone Derivative: Comprehensive Spectroscopic Approach toward Drug Discovery
2014 / Polyhedron
The title water-soluble thiol-capped QDs (quantum dots) were synthesized by reacting CdCl2, DMPS and NaHTe in a water medium [DMPS… Continue reading Synthesis, characterization and in vitro toxicity assessment of DMPS-capped CdTe quantum dots
2015 / Sensors and Actuators B: Chemical
A simple colorimetric and turn-on fluorescence receptor 1 was prepared and its cations and anions sensing properties were investigated in CH3CN solution.… Continue reading Discriminating detection between F− and CN− by naked eye from Schiff base sensor
2014 / Journal of Alloys and Compounds
Calcium zinc borophosphate glasses (CaZnBP) doped with various concentrations of Mn2+ ions and borate and phosphate as variable were prepared using… Continue reading Structural and luminescence properties of Mn2+ ions doped calcium zinc borophosphate glasses
2014 / Applied Catalysis B: Environmental
Graphitic carbon nitride (g-C3N4) was prepared by heating melamine and then its specific surface area was enlarged by hydrothermal treatment… Continue reading Complete oxidation of acetaldehyde over a composite photocatalyst of graphitic carbon nitride and tungsten(VI) oxide under visible-light irradiation
2018 / PLoS ONE
One of the major drawbacks of many of the currently used cancer drugs are off-target effects. Targeted delivery is one… Continue reading Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome c via a transferrin conjugate
2018 / Marine Drugs
Three new sesquiterpenoids (sinuketal (1), sinulins A and B (2 and 3)) and two new cembranoids (sinulins C and D (4 and 5)), as… Continue reading Terpenoids from the Soft Coral Sinularia sp. Collected in Yongxing Island
2018 / Scientific Reports
The first amphibian skin secretion-derived Bowman-Birk type chymotrypsin inhibitor is described here from the Asian green frog, Hylarana erythraea, and was… Continue reading A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea
2018 / American Society of Microbiology
Polymyxins, a family of cationic antimicrobial cyclic peptides, act as a last line of defense against severe infections by Gram-negative… Continue reading An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance
2018 / Nanomaterials
The unique biological features of supramolecular DNA have led to an increasing interest in biomedical applications such as biosensors. We… Continue reading Reversible Redox Activity by Ion-pH Dually Modulated Duplex Formation of i-Motif DNA with Complementary G-DNA
2018 / The Journal of Organic Chemistry
A nonplanar macrocycle consisting of four pyridine–acetylene–phenol units was developed as a host for saccharide guest molecules. The macrocycle was… Continue reading Nonplanar Macrocycle Consisting of Four Pyridine and Phenol Units Connected with Acetylene Bonds Displaying Preferential Binding to Maltoside over Monosaccharides
2018 / Journal of Natural Products
A chemical investigation of the ascomycetes of Daldinia concentrica was performed using silica gel column chromatography, ODS column chromatography, and preparative HPLC.… Continue reading Isoindolinones, Phthalides, and a Naphthoquinone from the Fruiting Body of Daldinia concentrica
2018 / PLoS Pathogens
The exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of… Continue reading A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency
2018 / RSC Advances
Polyethyleneimine (PEI) complexed with chiral D- (or L-) tartaric acid (tart) in water can self-organize into chiral and crystalline PEI/tart assemblies. It… Continue reading Convenient chirality transfer from organics to titania: construction and optical properties
2018 / Biochemistry and Biophysics Reports
Binding of recombinant prion protein with small highly structured RNAs, prokaryotic and eukaryotic prion protein mRNA pseudoknots, tRNA and polyA… Continue reading A quantitative characterization of interaction between prion protein with nucleic acids
2018 / Nucleic Acids Research
Guanine-rich DNA has the potential to fold into non-canonical G-quadruplex (G4) structures. Analysis of the genome of the social amoeba… Continue reading Quadruplexes in ‘Dicty’: crystal structure of a four-quartet G-quadruplex formed by G-rich motif found in the Dictyostelium discoideum genome
2018 / Polymer Chemistry
Proline and valine exist in repetitive motifs in various structural proteins and play an important role in their physiological functions.… Continue reading Chemoenzymatic synthesis of polypeptides consisting of periodic di- and tri-peptide motifs similar to elastin
2018 / Gels
Because the factors favoring the formation of well-formed single crystals are dissimilar to those conducive to gel formation, few examples… Continue reading Non-Steroidal Biphenyl Gelators: Correlation of Xerogel Structure with Solid-State Structure and Circular Dichroism Spectroscopy
2018 / Nanotechnology
Biological feedback mechanisms exert precise control over the initiation and termination of molecular self-assembly in response to environmental stimuli, while… Continue reading Force and time-dependent self-assembly, disruption and recovery of supramolecular peptide amphiphile nanofibers
