Found 9617 Results / Page 292 of 481
2018 / Analytical and Bioanalytical Chemistry
Luminol, horseradish peroxidase (HRP), and glucose oxidase (GOx) ternary functionalized graphene oxide (HRP/GOx-luminol-GO) with excellent chemiluminescence (CL) activity and specific… Continue reading Luminol, horseradish peroxidase, and glucose oxidase ternary functionalized graphene oxide for ultrasensitive glucose sensing
2017 / Biochemistry
Previously, we demonstrated that binding of a ligand to Escherichia coli cofactor-dependent phosphoglycerate mutase (dPGM), a homodimeric protein, is energetically coupled with… Continue reading A Cooperative Folding Unit as the Structural Link for Energetic Coupling within a Protein
2018 / Inorganic Chemistry Frontiers
The chiral recognition of racemic α-hydroxy/amino acids is an essential and challenging mission because enantiomers may profoundly differ in biological… Continue reading Chiral metal–organic frameworks constructed from four-fold helical chain SBUs for enantioselective recognition of α-hydroxy/amino acids
2018 / ChemBioChem
There are many biotechnology applications that would benefit from simple, stable proteins with engineered biomolecular recognition. Here, we explored the… Continue reading Engineered Biomolecular Recognition of RDX by Using a Thermostable Alcohol Dehydrogenase as a Protein Scaffold
2017 / Nature Communications
The microtubule-associated protein Tau plays a central role in the pathogenesis of Alzheimer’s disease. Although Tau interaction with membranes is… Continue reading Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes
2017 / PNAS
The presence of anomalous chirality in a roll of graphitic carbon sheets has been recognized since the discovery of carbon… Continue reading Chiral intertwined spirals and magnetic transition dipole moments dictated by cylinder helicity
2017 / Journal of Molecular Recognition
In our study, we have characterized the prefibrillar aggregates of human serum albumin (HSA) induced by temsirolimus, anti-renal cancer drug.… Continue reading Global transition of human serum albumin to prefibrillar aggregates induced by temsirolimus: Insight into implications of anti-renal cancer drug
2017 / Chirality
Chiral properties of surface complexes based on CdSe/ZnS quantum dots (QDs) and 1-(2-pyridylazo)-2-naphthol (PAN) azo dye were investigated by circular… Continue reading Circular dichroism of surface complexes based on quantum dots and azo dye
2017 / Journal of Medicinal Chemistry
Antimicrobial peptides are short peptides secreted by the innate immune system to protect the host from pathogens. We have investigated… Continue reading Amino Terminal Copper and Nickel Binding Motif Derivatives of Ovispirin-3 Display Increased Antimicrobial Activity via Lipid Oxidation
2017 / Scientific Reports
The abuse of antibiotics for disease treatment has led to the emergence of multidrug resistant bacteria. Antimicrobial peptides, found naturally… Continue reading Macropis fulvipes Venom component Macropin Exerts its Antibacterial and Anti-Biofilm Properties by Damaging the Plasma Membranes of Drug Resistant Bacteria
2017 / The Journal of Physical Chemistry B
Recently, a 3-hydroxychromone based nucleoside 3HCnt has been developed as a highly environment-sensitive nucleoside surrogate to investigate protein–DNA interactions. When… Continue reading Structural and Dynamical Impact of a Universal Fluorescent Nucleoside Analogue Inserted Into a DNA Duplex
2018 / Cytoskeleton
Proteins predicted to be composed of large stretches of coiled-coil structure have often proven difficult to crystallize for structural determination.… Continue reading Production of recombinant human tektin 1, 2, and 4 and in vitro assembly of human tektin 1
2018 / Phytochemistry
A phytochemical investigation on the aerial part of Euphorbia helioscopia(Euphorbiaceae) led to the isolation of 22 highly oxygenated diterpenoids with structural types of ent-abietane, ent-kaurane,… Continue reading Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia
2017 / Scientific Reports
Human flavin-containing monooxygenase 3 (hFMO3) catalyses the oxygenation of a wide variety of compounds including drugs as well as dietary… Continue reading Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine
2017 / Investigational New Drugs
Polymeric nanoparticles based on cyclodextrins are currently undergoing clinical trials as new promising nanotherapeutics. In light of this interest, we… Continue reading Cyclodextrin polymers as nanocarriers for sorafenib
2017 / Scientific Reports
Plants adapt to fluctuating light conditions by a process called non-photochemical quenching (NPQ), where membrane protein PsbS plays a crucial… Continue reading Large-scale in vitro production, refolding and dimerization of PsbS in different microenvironments
2017 / Nature Communications
Spinocerebellar ataxia type 5 (SCA5) is a neurodegenerative disease caused by mutations in the cytoskeletal protein β-III-spectrin. Previously, a SCA5… Continue reading Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation
2017 / Inorganic Chemistry
Molecular aggregation of bis(salicylaldiminato) ZnII Schiff base, ZnL, complexes is a topic of current interest. In this paper, we report a… Continue reading Aggregates of Defined Stereochemical Scaffolds: A Study in Solution of a Zinc(II) Schiff Base Complex Derived from the Enantiopure trans-1,2-Cyclopentanediamine
2018 / Colloids and Surfaces B: Biointerfaces
Cell-penetrating peptides (CPPs) have been applied as novel transport systems with the ability to facilitate the delivery of peptides, proteins,… Continue reading OBP fused with cell-penetrating peptides promotes liposomal transduction
2018 / New Journal of Chemistry
Here, we have reported three novel copper(II) complexes (1–3) involving azo Schiff base ligands. All the complexes have been well… Continue reading Syntheses, crystal structures, DNA binding, DNA cleavage, molecular docking and DFT study of Cu(II) complexes involving N2O4 donor azo Schiff base ligands
