Found 9617 Results / Page 295 of 481
2017 / Scientific Reports
Examples of bioactive peptides derived from internal sequences of proteins are known for decades. The great majority of these findings… Continue reading Encrypted Antimicrobial Peptides from Plant Proteins
2017 / Luminescence
Piperlongumine (PL) is a very promising natural agent with a high potential for cancer treatment. To overcome the poor water… Continue reading Spectroscopic investigation of the anticancer alkaloid piperlongumine binding to human serum albumin from the viewpoint of drug delivery
2017 / Scientific Reports
The major outer sheath protein (MOSP) is a prominent constituent of the cell envelope of Treponema denticola (TDE) and one of its… Continue reading The major outer sheath protein forms distinct conformers and multimeric complexes in the outer membrane and periplasm of Treponema denticola
2018 / European Journal of Medicinal Chemistry
A novel series of indole and benzimidazole bichalcophene diamidine derivatives were prepared to study their antimicrobial activity against the tropical… Continue reading Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity
2017 / Journal of Chemical Ecology
In light of reverse chemical ecology, the fluorescence competitive binding assays of functional odorant binding proteins (OBPs) is a recent… Continue reading Structural Transformation Detection Contributes to Screening of Behaviorally Active Compounds: Dynamic Binding Process Analysis of DhelOBP21 from Dastarcus helophoroides
2017 / Bioresources and Bioprocessing
In recent years, ionic liquids and enzymes have been widely used in the separation and extraction processes of natural products.… Continue reading Ionic liquid-based enzyme-assisted extraction of chlorogenic acid from Flos Lonicera Japonicae
2018 / Molecular Biotechnology
The substitutions of the amino acid at the predetermined critical point at the C-terminal of L2 lipase may increase its… Continue reading The Effects of One Amino Acid Substitutions at the C-Terminal Region of Thermostable L2 Lipase by Computational and Experimental Approach
2017 / Chemical Papers
Interaction of two mononuclear tetracoordinate complexes [Co(dmphen)Br2] and [Co(dmphen)I2] (dmphen = 2,9-dimethyl-1,10-phenanthroline), which have been recently reported to behave as single-molecule magnets… Continue reading Tetracoordinate cobalt(II) complexes with neocuproine: single-molecule magnets with potential biological activity
2018 / European Journal of Medicinal Chemistry
A series of new β-carboline-bisindole compounds were designed, synthesized and evaluated for their antiproliferative activity against human cancer cell lines, such as A549… Continue reading Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors
2017 / Nucleic Acids Research
G-quadruplexes (G4) within oncogene promoters are considered to be promising anticancer targets. However, often they undergo complex structural rearrangements that… Continue reading Conformational profiling of a G-rich sequence within the c-KIT promoter
2017 / Langmuir
Because uncontrolled accumulation of collagen fibrils has been implicated in a series of pathologies, inhibition of collagen fibril formation has… Continue reading Strategically Designed Antifibrotic Gold Nanoparticles to Prevent Collagen Fibril Formation
2017 / Fitoterapia
Seven new phloroglucinol derivatives, uraliones L-R (1–7), were isolated from the whole plant of Hypericum urialum. The structures of new compounds… Continue reading New phloroglucinol derivatives from the whole plant of Hypericum uralum
2017 / Biochemistry
Intrinsic disorder is a major structural category in biology, accounting for more than 30% of coding regions across the domains… Continue reading Hidden Structural Codes in Protein Intrinsic Disorder
2017 / Biochemical Journal
Onconase® (ONC), extracted by the oocytes of the frog Rana Pipiens , is a monomeric member of the secretory “pancreatic-type” RNase super-family.… Continue reading Onconase Dimerization Through 3D Domain Swapping: Structural Investigations and Increase Of The Apoptotic Effect In Cancer Cells
2017 / Biochimica et Biophysica Acta (BBA) - Biomembranes
For the first time, the photoisomerization of a diarylethene moiety (DAET) in peptideconjugates was used to probe the effects of molecular… Continue reading Flexibility vs rigidity of amphipathic peptide conjugates when interacting with lipid bilayers
2017 / Biochemical Journal
Calmodulin (CaM) is an intracellular Ca2+ transducer involved in numerous activities in a broad Ca2+signaling network. Previous studies have suggested that… Continue reading Direct Visualization of Interaction between Calmodulin and Connexin45
2017 / Allergy
Art v 1, Amb a 4, and Par h 1 are allergenic defensin-polyproline–linked proteins present in mugwort, ragweed, and feverfew… Continue reading Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity
2017 / PLoS ONE
Kisspeptin 1 is a neuropeptide hormone of the RFamide family, which act as an upstream regulator of brain-pituitary-gonad (BPG) axis… Continue reading Conformational analysis of a synthetic fish kisspeptin 1 peptide in membrane mimicking environments
2017 / RSC Advances
A series of discotic tricarboxyamides with varied amino acid side arm functionality and their HCl responsive diverse self-assembly behavior and… Continue reading Dynamic self-assembled polymer: HCl responsive inversion of supramolecular polymer handedness
2017 / Applied Biochemistry and Biotechnology
High xylanase activity and stability toward alkaline pH is strongly desired for pulping and bleaching processes. We previously enhanced thermal… Continue reading Laboratory Evolution of Bacillus circulans Xylanase Inserted into Pyrococcus furiosus Maltodextrin-Binding Protein for Increased Xylanase Activity and Thermal Stability Toward Alkaline pH
