Found 9617 Results / Page 362 of 481
2016 / Chemistry of Materials
Cellulose nanocrystals (CNCs) form cholesteric films that exhibit birefringence, iridescence, and circular dichroism, however these films are brittle and prone… Continue reading Composite Cholesteric Nanocellulose Films with Enhanced Mechanical Properties
2016 / Scientific Reports
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with aggregation of TAR DNA-binding protein-43 (TDP-43) in neuronal cells… Continue reading An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models
2016 / Scientific Reports
Seven new formyl phloroglucinol meroterpenoids (FPMs), namely eucalrobusones J-P (1–7), as well as three known ones (8–10) were isolated from… Continue reading New Formyl Phloroglucinol Meroterpenoids from the Leaves of Eucalyptus robusta
2016 / The Journal of Physical Chemistry C
DNA based materials are promising avenues for designing optical sensors, light harvesting device, energy conversion device and other potential applications.… Continue reading Silver (I) Induced Conformation Change of DNA: Gold Nanocluster as Spectroscopic Probe
2016 / PNAS
Parkinson’s disease is a devastating neurodegenerative disorder that can be inherited through mutations in genes encoding the kinase PTEN-induced kinase… Continue reading Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation
2016 / Scientific Reports
Circular Dichroism data are often decomposed into their constituent spectra to quantify the secondary structure of peptides or proteins but… Continue reading Simultaneous Analysis of Secondary Structure and Light Scattering from Circular Dichroism Titrations: Application to Vectofusin-1
2016 / Food Biophysics
Ligupurpuroside A is a glycoside extracted from Ku-Ding tea. As extracts from Ku-Ding tea exhibit anti-inflammatory property, we hypothesize that… Continue reading Mechanism and Nature of Inhibition of Trypsin by Ligupurpuroside A, a Ku-Ding Tea Extract, Studied by Spectroscopic and Docking Methods
2016 / Scientific Reports
There are hundreds of ligands which can interact with G-quadruplex DNA, yet very few which target i-motif. To appreciate an… Continue reading Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences
2016 / Scientific Reports
Tyrosine hydroxylase (TH), a rate-limiting enzyme in the synthesis of catecholamine neurotransmitters and hormones, binds to negatively charged phospholipid membranes.… Continue reading Tyrosine Hydroxylase Binding to Phospholipid Membranes Prompts Its Amyloid Aggregation and Compromises Bilayer Integrity
2017 / Archives of Insect Biochemistry and Physiology
In present study, a Cecropin-like peptide from Antheraea pernyi (ApCec) was cloned and characterized. The full-length ApCec cDNA encoded a protein with 64… Continue reading Characterization and functional study of a Cecropin-like peptide from the Chinese oak silkworm, Antheraea pernyi
2016 / The FEBS Journal
The vitamin B6 salvage pathway, involving pyridoxine 5′-phosphate oxidase (PNPOx) and pyridoxal kinase (PLK), recycles B6 vitamers from nutrients and protein turnover… Continue reading Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B6 salvage pathway
2017 / Catalysts
Protein digestion by trypsin has been widely used in many industrial and research applications. However, extensive use of trypsin is… Continue reading Synthesis and Characterization of Highly Stabilized Polymer–Trypsin Conjugates with Autolysis Resistance
2017 / Molecules
Pathological states in the organism, e.g., renal or hepatic diseases, cataract, dysfunction of coronary artery, diabetes mellitus, and also intensive… Continue reading Spectroscopic Studies on the Molecular Ageing of Serum Albumin
2016 / Biochemistry
Short hydrogen bonds (H-bonds) have been proposed to play key functional roles in several proteins. The location of the proton… Continue reading Short Carboxylic Acid–Carboxylate Hydrogen Bonds Can Have Fully Localized Protons
2016 / Protein Science
MPT63, a major secreted protein from Mycobacterium tuberculosis, has been shown to have immunogenic properties and has been implicated in virulence. MPT63… Continue reading The Presence of Non-Native Helical Structure in the Unfolding of a Beta Sheet Protein MPT63
2016 / Scientific Reports
Piperine, a naturally occurring alkaloid, is well known as anti-oxidant, anti-mutagenic, anti-tumor and anti-proliferative agent. Piperine exerts such pharmacological activities… Continue reading Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences
2016 / Biophysical Journal
Protein-protein interactions play a critical role in promoting the stability of protein quaternary structure and in the assembly of large macromolecular… Continue reading Heterotypic Coiled-Coil Formation is Essential for the Correct Assembly of the Septin Heterofilament
2016 / PLoS ONE
Cruciferous vegetables contain the bio-active compound sulforaphane (SF) which has been reported to protect individuals against various diseases by a… Continue reading Activation of Human Salivary Aldehyde Dehydrogenase by Sulforaphane: Mechanism and Significance
2017 / Biomaterials
The integration of a targeted delivery with a tumour-selective agent has been considered an ideal platform for achieving high therapeutic… Continue reading Genetically engineered and self-assembled oncolytic protein nanoparticles for targeted cancer therapy
2017 / International Journal of Biological Macromolecules
Glycation of ocular lens proteins plays a vital role in the development of diabetic cataract. In order to investigate the… Continue reading Glycation of human γB-crystallin: A biophysical investigation
