Atypical angiogenesis is one of the major symptoms of severe eye diseases, including corneal neovascularization, and the complex nature of… Continue reading Inhibition of VEGF mediated corneal neovascularization by anti-angiogenic peptide nanofibers
Leah Pandiscia, PhD
July 28, 2017
Phytochemical and pharmacological study on the rhizomes of Atractylodes lancea led to the identification of twenty-one compounds: six new eudesmane-type sesquiterpenoids (1–6),… Continue reading Eight new eudesmane- and eremophilane-type sesquiterpenoids from Atractylodes lancea
Leah Pandiscia, PhD
July 28, 2017
DNA guanine-quadruplexes (G-quadruplexes) complexed with the Fe-containing porphyrin, hemin (iron(III)-protoporphyrin IX), can catalyze oxidation reactions. This so-called DNAzyme has been… Continue reading Volumetric analysis of formation of the complex of G-quadruplex DNA with hemin using high pressure
Leah Pandiscia, PhD
July 28, 2017
Antimalarial bioassay-guided fractionation of the swamp lily Crinum erubescens led to the isolation of four compounds with potent antiplasmodial activity. Compounds 1 and 2were determined… Continue reading New potently bioactive alkaloids from Crinum erubescens
Leah Pandiscia, PhD
July 28, 2017
Methyl pyropheophorbides-a possessing a (pseudo)planar substituent at the 3-position were prepared from naturally occurring chlorophyll-a. Some of the semisynthetic π-conjugates with… Continue reading Rotational isomerization of 3-substituents in synthetic chlorophyll derivatives
Leah Pandiscia, PhD
July 28, 2017
A series of chiral and achiral neutral vanadyl complexes with N-heterocycle chelated ligands [V2O2(S-lact)2(bpy)2] (1), [V2O2(S-lact)2(phen)2] (2), [V2O2(R-lact)(S-lact)(bpy)2] (3), [V2O2(R-lact)(S-lact)(phen)2]… Continue reading Chiral and achiral vanadyl lactates with vibrational circular dichroism: Toward the chiral metal cluster in nitrogenase
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The structure and catalytic activity of xylanase from Thermomyces lanuginosus were studied in different media (containing polyethylene glycol -PEG- or salt) at… Continue reading Partitioning of xylanase from Thermomyces lanuginosus in PEG/NaCit aqueous two-phase systems: Structural and functional approach
Leah Pandiscia, PhD
July 28, 2017
Beta_defensin have been solely found in vertebrates until β-defensin-like peptides were described as transcript isoforms in two species of Panulirus genus. They… Continue reading Panusin represents a new family of β-defensin-like peptides in invertebrates
Leah Pandiscia, PhD
July 28, 2017
A series of novel copper (II) and nickel (II) complexes derived from chiral Schiff-base ligands [(R)/(S)-H2L1 = (R)/(S)-2-[(1-Hydroxymethyl-propylimino)-methyl]-5-methoxy-phenol and (R)/(S)-H2L2 = (R)/(S)-2-[(1-Hydroxymethyl-2-phenyl-ethylimino)-methyl]-5-methoxy-phenol],… Continue reading Cu(II), Ni(II) Complexes Derived from Chiral Schiff-base Ligands: Synthesis, Characterization, Cytotoxicity, Protein and DNA–binding Properties
Leah Pandiscia, PhD
July 28, 2017
Potassium channel tetramerization domain containing 1 (KCTD1) family members have a BTB/POZ domain, which can facilitate protein-protein interactions involved in… Continue reading Bivalent Copper Ions Promote Fibrillar Aggregation of KCTD1 and Induce Cytotoxicity
Leah Pandiscia, PhD
July 28, 2017
We have developed a two-photon fluorescent tracer (Pyr-affibody) that shows high selectivity for human epidermal growth factor receptor-2 (HER-2). Pyr-affibody… Continue reading A two-photon tracer for human epidermal growth factor receptor-2: Detection of breast cancer in a live tissue
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The unicellular cyanobacterium Cyanothece sp. CCY 0110 is a highly efficient producer of extracellular polymeric substances (EPS), releasing up to… Continue reading Cyanobacterium-Derived Extracellular Carbohydrate Polymer for the Controlled Delivery of Functional Proteins
Leah Pandiscia, PhD
July 28, 2017
The refolding of urea denatured horse heart cytochrome c (h-cyt-c) under the influence of ester based cationic gemini surfactants [ethane-1, 2-diyl bis(N, N-dimethyl-N-alkylammoniumacetoxy)… Continue reading Refolding of urea denatured cytochrome c: Role of hydrophobic tail of the cationic gemini surfactants
Leah Pandiscia, PhD
July 28, 2017
The immobilization of antimicrobial peptides (AMPs) to surfaces, enabling their utilization in biosensor and antibacterial/antifouling coating applications, is typically performed… Continue reading Bactericidal Hydrogels via Surface Functionalization with Cecropin A
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Amyloids are polymeric structural states formed from locally or totally unfolded protein chains that permit surface reorganizations, stability enhancements and… Continue reading The amyloid fold of Gad m 1 epitopes governs IgE binding
Leah Pandiscia, PhD
July 28, 2017