Found 9617 Results / Page 393 of 481
2016 / RSC Advances
(+)-Mahanimbine (1), a prenylated carbazole alkaloid, was isolated from the stems of Murraya koenigii. Herein we developed a divergent synthesis by… Continue reading Divergent synthesis of prenylated carbazole alkaloid (+)-S-mahanimbine led to the discovery of a notch activator
2016 / RSC Advances
As an emerging nanomaterial, quantum dots (QDs) have received enormous attention for their excellent photophysical properties. However, their biotoxicity restricts… Continue reading Influence of mercaptopropionic-acid-capped CdTe quantum dots on the human chorionic gonadotropin structure and activity alterations
2016 / Macromolecular Bioscience
Extracellular matrix (ECM), comprised of multiple cues (chemical, physiomechanical), provides a niche for cell attachment, migration, and differentiation. Given that… Continue reading Tunable Crosslinked Cell-Derived Extracellular Matrix Guides Cell Fate
2016 / RSC Advances
The interaction of anti-tuberculosis drug pyrazinamide (PYZ) with serum albumins (HSA and BSA) has been studied using spectroscopic and molecular… Continue reading Comparative binding study of anti-tuberculosis drug pyrazinamide with serum albumins
2016 / New Journal of Chemistry
A new Pd(II) complex, [Pd(4-OHPh-tpy)Cl]Cl, with a ligand that is a terpyridine derivative, (4′-(4-hydroxyphenyl)-2,2′,6′,2′′-terpyridine (4-OHPh-tpy)), was prepared and fully characterized.… Continue reading A water-soluble Pd(II) complex with a terpyridine ligand: experimental and molecular modeling studies of the interaction with DNA and BSA; and in vitrocytotoxicity investigations against five human cancer cell lines
2016 / Clinical & Experimental Allergy
Nociceptin/orphanin FQ (N/OFQ) and its receptor (NOP) are involved in airway hyperresponsiveness (AHR) and inflammation. However the role of nociceptin… Continue reading Nociceptin reduces the inflammatory immune microenvironment in a conventional murine model of airway hyperresponsiveness
2016 / Inorganic Chemistry Frontiers
A chiral Cu(II) metal–organic framework, [H2N(CH3)2]2[Cu(L)]·5.5DMF (1), was constructed using a diisophthalate ligand with an active pyridyl site, 2,6-di(3′,5′-dicarboxylphenyl)pyridine (H4L).… Continue reading A chiral metal–organic framework with polar channels: unique interweaving six-fold helices and high CO2/CH4 separation
2016 / Nucleic Acids Research
Recently, highly lipophilic S-geranylated derivatives of 5-methylaminomethyl-2-thiouridine (mnm5geS2U) and 5-carboxymethylaminomethyl-2-thiouridine (cmnm5geS2U) were found at the first (wobble) anticodon position in bacterial… Continue reading S-Geranyl-2-thiouridine wobble nucleosides of bacterial tRNAs; chemical and enzymatic synthesis of S-geranylated-RNAs and their physicochemical characterization
2016 / Scientific Reports
Unwanted clots lead to heart attack and stroke that result in a large number of deaths. Currently available anticoagulants have… Continue reading Exactin: A specific inhibitor of Factor X activation by extrinsic tenase complex from the venom of Hemachatus haemachatus
2016 / Biochemical and Biophysical Research Communications
Sortase mediated transpeptidation reactions play a significant role in covalent attachment of surface proteins to the cell wall of Gram-positive… Continue reading Active site analysis of sortase A from Staphylococcus simulansindicates function in cleavage of putative cell wall proteins
2016 / BMC Biology
The Cry6 family of proteins from Bacillus thuringiensis represents a group of powerful toxins with great potential for use in… Continue reading The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins
2016 / Chemico-Biological Interactions
Harmalol administration caused remarkable reduction in proliferation of HepG2 cells with GI50 of 14.2 μM, without showing much cytotoxicity in embryonic liver cell… Continue reading DNA binding and apoptotic induction ability of harmalol in HepG2: Biophysical and biochemical approaches
2016 / Phytochemistry
Phytochemical investigation of the ethanolic extract of Grangea maderaspatana led to isolation of gramaderins A–D, together with thirteen known compounds. All isolates… Continue reading Diterpenes from Grangea maderaspatana
2016 / PLoS ONE
G-quadruplex forming sequences are particularly enriched in the promoter regions of eukaryotic genes, especially of oncogenes. One of the most… Continue reading Discovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression
2016 / Tetrahedron
From stromata (fruiting bodies) of three xylariaceous fungi belonging to the genusAnnulohypoxylon (A. leptascum, A. cf. truncatum and an unidentified Annulohypoxylonsp.), truncatone A (1), three… Continue reading Truncatones A–D, benzo[j]fluoranthenes fromAnnulohypoxylon species (Xylariaceae, Ascomycota)
2016 / International Journal of Biological Macromolecules
The GH10 endo-xylanase from Thermoascus aurantiacus CBMAI 756 (XynA) is industrially attractive due to its considerable thermostability and high specific activity. Considering the… Continue reading Engineering increased thermostability in the GH-10 endo-1,4-β-xylanase from Thermoascus aurantiacus CBMAI 756
2016 / Polymer
Inspired by jellyfish, this article reports a novel type of GO-derived reversible transition hybrid material, in which optically active helical… Continue reading Bioinspired hybrid material composed of helical polymer grafts and graphene oxide: Reversible transformation of particulate and extended structures of the grafts and application in chiral enrichment
2016 / Acta Biomaterialia
The control of the interactions of proteins with the support matrix plays a key role in medicine, drug delivery systems… Continue reading Conformational control of human transferrin covalently anchored to carbon-coated iron nanoparticles in presence of a magnetic field
2016 / International Journal of Biological Macromolecules
Keratins as fibrous proteins, offer structural integrity to various tissues in providing the functional role of protection or load bearing.… Continue reading Transient Structures of Keratins from Hoof and Horn Influence Their Self Association and Supramolecular Assemblies
2017 / Materials Science and Engineering: C
Two novel imidazole derived Schiff bases, (Z)-1-(1H-benzo[d]imidazol-2-yl)-N-benzylidenemethanamine (L1) and 1-(1H-benzo[d]imidazol-2-yl)-N-(4-nitrobenzylidene) methanamine, and a series of their transition metal complexes of… Continue reading A treatise on benzimidazole based Schiff base metal(II) complexes accentuating their biological efficacy: Spectroscopic evaluation of DNA interactions, DNA cleavage and antimicrobial screening
