Found 9617 Results / Page 400 of 481
2016 / Analytica Chimica Acta
Two small molecules showed intriguing properties of analytical multipurpose probes, whereby one chromophore gives different signal for many different DNA/RNA… Continue reading Small molecule probes finely differentiate between various ds- and ss-DNA and RNA by fluorescence, CD and NMR response
2016 / Nature Chemical Biology
The structure-specific nuclease human flap endonuclease-1 (hFEN1) plays a key role in DNA replication and repair and may be of… Continue reading Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site
2016 / A European Journal of Chemical Physics and Physical Chemisty
The ability to precisely and remotely modulate reversible binding interactions between biomolecules and abiotic surfaces is appealing for many applications.… Continue reading Optical Modulation of Azobenzene-Modified Peptide for Gold Surface Binding
2016 / Journal of Solid State Electrochemistry
The direct electrochemistry and electrocatalysis of cytochrome c (Cyt c) based on dandelion-like bismuth sulfide (d-Bi2S3) nanoflowers have been developed. The morphologies and… Continue reading Direct electrochemistry and electrocatalysis of cytochrome c based on dandelion-like Bi2S3nanoflowers
2016 / Analytica Chimica Acta
Peptides and proteins have become very promising drug candidates in recent decades due to their unique properties. However, the application… Continue reading Determination of the composition, encapsulation efficiency and loading capacity in protein drug delivery systems using circular dichroism spectroscopy
2016 / Journal of Chromatography A
The distinct activity and toxicity of enantiomers has increased concern about the use of chiral pesticides. The chiral pesticide Fenamiphos… Continue reading In-line coupling of an achiral-chiral column to investigate the enantioselective in vitro metabolism of the pesticide Fenamiphos by human liver microsomes
2016 / Scientific Reports
DehI is a homodimeric haloacid dehalogenase from Pseudomonas putida that contains the most complex 61 Stevedore’s protein knot within its… Continue reading Folding analysis of the most complex Stevedore’s protein knot
2016 / A European Journal of Chemical Physics and Physical Chemisty
A 1:1 mixture of pseudoenantiomeric aminomethylenehelicene oligomers, (P)-tetramer and (M)-pentamer, in fluorobenzene show a self-catalytic phenomenon in the formation of… Continue reading Spatially Heterogeneous Nature of Self-Catalytic Reaction in Hetero-Double Helix Formation of Helicene Oligomers
2016 / Phytochemistry Letters
Two new hexahydrobenzo[c] phenanthridine alkaloids, ambiguanine H (1) and ambiguanine I (2) together with six known hexahydrobenzo[c] phenanthridine alkaloids (3–8),… Continue reading Protective effect of hexahydrobenzo[c]phenanthridine alkaloids isolated from Corydalis ambigua var. amurensis on myocardial ischemia-hypoxia cells
2016 / MedChemComm
Proteins show remarkable versatility as multifunctional materials for therapeutic applications. They can be easily modified with the toolkit of bioorganic… Continue reading Methods of protein surface PEGylation under structure preservation for the emulsion-based formation of stable nanoparticles
2016 / RSC Advances
Improvement in the in vitro and in vivo stability of biotherapeutic proteins has been approached viaa number of strategies, including protein PEGylation or formulation with… Continue reading Impact of PEGylation and non-ionic surfactants on the physical stability of the therapeutic protein filgrastim (G-CSF)
2016 / Scientific Reports
A supramolecular porphyrin nanotube displaying J-aggregation feature was constructed by out-ofplane coordinated bismuth-porphyrin. Significantly, compared to traditional J-aggregated porphyrin suffering… Continue reading Out-of-Plane Coordinated Porphyrin Nanotubes with Enhanced Singlet Oxygen Generation Efficiency
2016 / Journal of Photochemistry and Photobiology B: Biology
Bisphenol A is widely used in the manufacture of food packaging and beverage containers and can invade our food and… Continue reading Deciphering the toxicity of bisphenol a to Candida rugosa lipase through spectrophotometric methods
2016 / Dyes and Pigments
Molecules capable of inducing self-structure in poly(A) may arrest protein synthesis by preventing poly(A) chain elongation thereby inhibiting the function… Continue reading Spectroscopic, calorimetric, cyclic voltammetric and molecular modeling studies of new methylene blue-polyadenylic acid interaction and comparison to thionine and toluidine blue O: Understanding self-structure formation by planar dyes
2016 / Biochimica et Biophysica Acta (BBA) - Biomembranes
Membrane-active peptides (MAPs), which interact directly with the lipid bilayer of a cell and include toxins and host defense peptides,… Continue reading The Interaction of Melittin with Dimyristoyl Phosphatidylcholine-Dimyristoyl Phosphatidylserine Lipid Bilayer Membranes
2016 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
The cytosolic and mitochondrial isoforms of serine hydroxymethyltransferase (SHMT1 and SHMT2, respectively) are well-recognized targets of cancer research, since their… Continue reading Differential 3-Bromopyruvate Inhibition of Cytosolic and Mitochondrial Human Serine Hydroxymethyltransferase Isoforms, Key Enzymes in Cancer Metabolic Reprogramming
2016 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
KRAS promoter can form G-quadruplex structure and regulate gene transcription. The drugs which can bind with G-quadruplex of KRAS promoter may be potential… Continue reading Spectroscopic investigation of the interaction between G-quadruplex of KRAS promoter sequence and three isoquinoline alkaloids
2016 / Biochimie
Snake venom Kunitz-type serine protease inhibitors (KSPIs) exhibit various biological functions including anticoagulant activity. This study elucidates the occurrence and… Continue reading Structural and functional characterization of complex formation between two Kunitz-type serine protease inhibitors from Russell’s Viper venom
2016 / Biosensors and Bioelectronics
Norovirus is known as the major cause of highly infection for gastrointestinal tracts. In this study, robust and highly sensitive… Continue reading High sensitive and selective electrochemical biosensor: Label-free detection of human norovirus using affinity peptide as molecular binder
2016 / Innovative Food Science & Emerging Technologies
The ultrasound treatment on whey protein before enzymatic hydrolysis using vegetable proteases was studied. Ultrasound density, temperature, and pretreatment time… Continue reading Impact of ultrasound pretreatment on whey protein hydrolysis by vegetable proteases
