Poly(vinylamine-co-N-vinylisobutylamide) or poly(VAm-co-NVIBA) was evaluated for its ability to stabilize double-stranded DNA (dsDNA) with the controlled formation or dissociation of… Continue reading Controlled DNA interpolyelectrolyte complex formation or dissociation via stimuli-responsive poly(vinylamine-co-N-vinylisobutylamide)
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Biosynthesis of L-tyrosine (L-Tyr) and L-phenylalanine (L-Phe) is directed by the interplay of three enzymes. Chorismate mutase (CM) catalyzes the… Continue reading Characterization of two key enzymes for aromatic amino acid biosynthesis in symbiotic archaea
Leah Pandiscia, PhD
July 28, 2017
Both Met104 and Met105 are involved, either directly or indirectly, in the redox mediated ligand switch of the heme-dependent transcription factor, RcoM-1.… Continue reading Met104 is the CO-replaceable ligand at Fe(II) heme in the CO-sensing transcription factor BxRcoM-1
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Carbon nanotubes (CNTs) with unique and outstanding properties were expected to revolutionize various aspects of the biomedical sector. Interaction studies… Continue reading Prion like behavior of HSA-hydroxylated MWCNT interface
Leah Pandiscia, PhD
July 28, 2017
The transcription factor p53 has a tumor suppressor role in leading damaged cells to apoptosis. Its activity is regulated/inhibited in… Continue reading Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Holins are pore-forming membrane proteins synthesized by lytic phages. The second transmembrane domain (TM2) of Mycobacteriophage D29 holin presents an… Continue reading Solvation Driven Conformational Transitions in the Second Transmembrane Domain of Mycobacteriophage Holin
Leah Pandiscia, PhD
July 28, 2017
The sole role of bradykinin (BK) as an inflammatory mediator is controversial, as recent data also support an anti-inflammatory role… Continue reading Copper, differently from zinc, affects the conformation, oligomerization state and activity of bradykinin
Leah Pandiscia, PhD
July 28, 2017
Bovine α-lactalbumin (α-La) is a major food allergen found in milk and is characterized by high conformational stability because of… Continue reading Potential allergenicity response to structural modification of irradiated bovine α-lactalbumin
Leah Pandiscia, PhD
July 28, 2017
Phytochemical investigation on the whole plants of Iris japonica led to the isolation of four new aromatic glycosides. Their structures including the… Continue reading Aromatic glycosides from the whole plants ofIris japonica
Leah Pandiscia, PhD
July 28, 2017
Three new lignanosides (+)-(8S,7′S,8′S)-burselignan-9′-O-β-d-glucopyrano side (1), (+)-(8R,7′S,8′R)-isolariciresinol-9′-O-β-d-fucopyranoside (2), (-)-(8S, 7′R,8′R)-methoxyisoariciresinol-9′-O-α-l-rhamnoside (3), along with four known compounds, were isolated from the… Continue reading Three new lignanosides from the aerial parts of Lespedeza cuneata
Leah Pandiscia, PhD
July 28, 2017
We explored the production of hydrazine from NO and ammonium by anammox biomass, which normally converts ammonium and nitrite to… Continue reading Hydrazine production by anammox biomass with NO reversible inhibition effects
Leah Pandiscia, PhD
July 28, 2017
The C-terminal region of the M-protein of Streptococcus pyogenes is a major target for vaccine development. The major feature is the C-repeat… Continue reading Predicted Coverage and Immuno-Safety of a Recombinant C-Repeat Region Based Streptococcus pyogenes Vaccine Candidate
Leah Pandiscia, PhD
July 28, 2017
Silk is useful as a drug carrier due to its biocompatibility, tunable degradation, and outstanding capacity in maintaining the function… Continue reading Injectable and pH-Responsive Silk Nanofiber Hydrogels for Sustained Anticancer Drug Delivery
Leah Pandiscia, PhD
July 28, 2017
Chiral carbon quantum dots (L-carbon quantum dots, L-CQDs; and D-carbon quantum dots, D-CQDs) were synthesized through the facile hydrothermal treatment of carbonated citric… Continue reading One-step synthesis of chiral carbon quantum dots and their enantioselective recognition
Leah Pandiscia, PhD
July 28, 2017
The pathogenic bacteria Legionella pneumophila is known to cause Legionnaires’ Disease, a severe pneumonia that can be fatal to immunocompromised individuals and… Continue reading Characterization of the structure and catalytic activity of Legionella pneumophila VipF
Leah Pandiscia, PhD
July 28, 2017
The effects of processing (dry-milling, cooking, isoelectric precipitation) on the physicochemical, functional and nutritional properties of lentil were evaluated. Protein,… Continue reading Comparative Study of the Effects of Processing on the Nutritional, Physicochemical and Functional Properties of Lentil
Leah Pandiscia, PhD
July 28, 2017
