Leah Pandiscia, PhD
July 28, 2017
We here report an experimental study on the thermal aggregation process of concanavalin A, a protein belonging to the legume… Continue reading Amyloid fibrils formation and amorphous aggregation in concanavalin A
Leah Pandiscia, PhD
July 28, 2017
The DNA binding properties of three cation-substituted anthrapyrazole derivatives of emodin with calf thymus DNA were characterized by spectroscopic methods… Continue reading Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin
Leah Pandiscia, PhD
July 28, 2017
The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluorescence sensor for chiral amines and amino alcohols. The fluorescence of HELIXOL… Continue reading 2,15-Dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor
Leah Pandiscia, PhD
July 28, 2017
The question of whether distinct self-propagating structures could be formed within the same amino acid sequence in the absence of… Continue reading The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States
Leah Pandiscia, PhD
July 28, 2017
Filamentous inclusions made of a-synuclein constitute the defining neuropathological characteristic of Parkinson’s disease, dementia with Lewy bodies, and multiple system… Continue reading Fiber diffraction of synthetic a-synuclein filaments shows amyloid-like cross-b conformation
Leah Pandiscia, PhD
July 28, 2017
Four new quercetin-derived oxidation products (1-4) and lunularin-4-O-â-D-glucoside (5) were isolated from a water extract of onion (Allium cepa) skin,… Continue reading Antibacterial and Antioxidant Activities of Quercetin Oxidation Products from Yellow Onion (Allium cepa) Skin
Leah Pandiscia, PhD
July 28, 2017
The intracellular deposition of fibrillar aggregates of α-synuclein is a characteristic feature of Parkinson disease. Alternatively, as a result of… Continue reading Binding of α-Synuclein Affects the Lipid Packing in Bilayers of Small Vesicles
Leah Pandiscia, PhD
July 28, 2017
A new approach for attaining sustained release of protein is introduced, involving a pore-closing process of preformed porous PLGA microspheres.… Continue reading Biodegradable polymeric microspheres with “open/closed” pores for sustained release of human growth hormone
Leah Pandiscia, PhD
July 28, 2017
The tripartite motif (TRIM) protein, TRIM5 , is an endogenous factor in primates that recognizes the capsids of certain retroviruses… Continue reading Biochemical and Biophysical Characterization of a Chimeric TRIM21-TRIM5α Protein
Leah Pandiscia, PhD
July 28, 2017
Linear dichroism (LD) can be used to study the alignment of absorbing chromophores within long molecules. In particular, Couette flow… Continue reading Micro-Volume Couette Flow Sample Orientation for Absorbance and Fluorescence Linear Dichroism
Leah Pandiscia, PhD
July 28, 2017
Death receptors (DRs) can induce apoptosis by oligomerization with TRAIL, whereas death decoy receptors (DcRs) cannot, due to their lack… Continue reading Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Phytochromes are a widespread family of photosensory proteins first discovered in plants, which measure the ratio of red to far-red… Continue reading Distinct classes of red/far-red photochemistry within the phytochrome superfamily
Leah Pandiscia, PhD
July 28, 2017
Two eudesmanes, two abietanes, two podocarpanes and other nine known compounds were isolated from the dried fruits of Juniperus polycarpus var. seravschanica. Their… Continue reading Terpenoids from Juniperus polycarpus var. seravschanica
Leah Pandiscia, PhD
July 28, 2017
2-Cysteine peroxiredoxins (2-CysPrxs) are ubiquitous and highly abundant proteins that serve multiple functions as peroxidases, chaperones, and thiol oxidases and… Continue reading The conformational bases for the two functionalities of 2-cysteine peroxiredoxins as peroxidase and chaperone
Leah Pandiscia, PhD
July 28, 2017
Denaturant-induced conformational change of yeast iso-1-cytochrome c (Cytc) has been comprehensively investigated in the single-molecule and bulk phases. By fluorescence-quenching experiments with dye-labelled heme-protein (Alexa… Continue reading Unfolding dynamics of cytochrome c revealed by single-molecule and ensemble-averaged spectroscopy
Leah Pandiscia, PhD
July 28, 2017
A novel nanocomposite based on TiO2–protein for functional applications was prepared and characterized. The composite was made by covalent immobilisation… Continue reading Nanocomposite based on modified TiO2–BSA for functional applications
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
