Found 9617 Results / Page 428 of 481
2016 / ChemMedChem
Iridium-based metal complexes containing polypyridyl-pyrazine ligands show properties of DNA intercalation. They serve as roadblocks to DNA polymerase activity, thereby… Continue reading Iridium Complexes as a Roadblock for DNA Polymerase during Amplification
2016 / Small
Controlled hierarchical self-assembly of synthetic molecules into chiral nanoarchitectures to mimic those biological chiral structures is of great importance. Here,… Continue reading Self-Assembly of Hierarchical Chiral Nanostructures Based on Metal–Benzimidazole Interactions: Chiral Nanofibers, Nanotubes, and Microtubular Flowers
2016 / Biochemistry
Interest in exploring G-quadruplex (G4) structures in nucleic acids is growing as it becomes more widely recognised that these structures… Continue reading Fluorescent methods for probing G-quadruplex structure in single and double stranded DNA
2016 / Journal of Photochemistry and Photobiology B: Biology
New copper(II)–based complex (1) was synthesized and characterized by analytical, spectroscopic and single crystal X–ray diffraction. The in vitro binding studies of… Continue reading Synthesis and crystal structure elucidation of new copper(II)–based chemotherapeutic agent coupled with 1,2–DACH and orthovaniline: Validated by in vitro DNA/HSA binding profile and pBR322 cleavage pathway
2016 / Toxicon
The presence of bioactive peptides in animal venoms has been targeted in scientific research for assessing biological activities, as well… Continue reading Characterization of TistH, a multifunctional peptide from the scorpion Tityus stigmurus: Structure, cytotoxicity and antimicrobial activity
2016 / Biotechnology and Bioengineering
A polymerase chain reaction (PCR) using a thermostable DNA polymerase is the most widely applied method in many areas of… Continue reading A repeat protein-based DNA polymerase inhibitor for an efficient and accurate gene amplification by PCR†
2016 / Colloids and Surfaces B: Biointerfaces
Interaction between charged BSA colloids and the buffer at air/fluid interface has been studied using spread films of the capsules… Continue reading Balancing soft elasticity and low surface polarity in films of charged BSA capsules at air/fluid interface
2016 / Nature Protocols
Despite the great importance of membrane proteins, structural and functional studies of these proteins present major challenges. A significant hurdle… Continue reading A method for detergent-free isolation of membrane proteins in their local lipid environment
2016 / Toxicon
The genes of the five disulfide-bonded peptide toxins 1 and 2 (named Oxytoxins or Oxotoxins) from the spider Oxyopes lineatus were cloned… Continue reading Heterologous expression of five disulfide-bonded insecticidal spider peptides
2016 / BIochimie
Some reports indicate that thymoquinone (TQ), the main constituent of Nigella sativaseeds, is hepatoprotective. The aim of this study was to… Continue reading Thymoquinone, an active constituent of Nigella sativa seeds, binds with bilirubin and protects mice from hyperbilirubinemia and cyclophosphamide-induced hepatotoxicity
2016 / Biomacromolecules
We previously reported the co-assembly of various proteins with poly(4-vinylpyridine) (P4VP) to form core-shell nanoparticles (CSNPs). However, P4VP suffers from… Continue reading Development of core-shell nanostructures by in situ assembly of pyridine-grafted diblock copolymer and transferrin for drug delivery applications
2016 / Inorganic Chemistry Communications
Four new inorganic–organic hybrid polyoxomolybdates K2[SeIVMo6O21(L-O2CCHNH3CH2OH)3]·6H2O (1) and K2[SeIVMo6O21(D-O2CCHNH3CH2OH)3]·6H2O (2), K2[TeIVMo6O21(D-O2 CCHNH3CH2OH)3]·6H2O (3) and K2[TeIVMo6O21(L-O2CCHNH3CH2OH)3]·6H2O (4) have been synthesized by a… Continue reading Syntheses, structures and properties of four inorganic–organic hybrid heteropolymolybdates functionalized by chiral serine ligands
2016 / Biochimica et Biophysica Acta (BBA) - Biomembranes
Yes. To understand the molecular mechanisms of amphiphilic membrane-active peptides, it is essential to study their interactions with lipid bilayers… Continue reading Does a methionine-to-norleucine substitution in PGLa influence peptide-membrane interactions?
2016 / Tetrahedron
Regioisomeric 3- and 8-vinylchlorins as well as 7- and 12-vinylchlorins were prepared by modifying naturally occurring chlorophylls-a and/or b. The corresponding formylchlorins… Continue reading Preparation of mono-vinylated and formylated chlorophyll derivatives and their optical properties
2016 / PLoS ONE
Recombinant human transforming growth factor beta-3 (rhTGF-β3) is a key regulator of chondrogenesis in stem cells and cartilage formation. We… Continue reading Extracellular Matrix (ECM) Multilayer Membrane as a Sustained Releasing Growth Factor Delivery System for rhTGF-β3 in Articular Cartilage Repair
2016 / RSC Advances
Withanolides are a large group of steroidal lactones found in Solanaceae plants that exhibit potential anticancer activities. In the present… Continue reading Cytotoxic withanolides from Physalis angulata var. villosa and the apoptosis-inducing effect via ROS generation and the activation of MAPK in human osteosarcoma cells
2016 / Environmental Science: Processes & Impacts
The binding study of pesticides with proteins is of great importance in ecotoxicology. In this study, a comparative interaction mechanism… Continue reading Spectroscopic evaluation of the interaction between pesticides and chickpea cystatin: comparative binding and toxicity analyses
2016 / Chinese Chemical Letters
Three new phenolics (1–3) and twenty-eight known compounds (4–31) were isolated from an ethanolic extract of roots of Alangium chinense. Compound 11 exhibited… Continue reading Phenolic constituents from the roots of Alangium chinense
2016 / Biochemical and Biophysical Research Communications
Chironomus ramosus is known to tolerate high doses of gamma radiation exposure. Larvae of this insect possess more than 95% of… Continue reading Differential sensitivity of Chironomus and human hemoglobin to gamma radiation
2016 / Analytical Chemistry
Smart and versatile nanostructures have demonstrated their effectiveness for biomolecule analysis and show great potential in digging insights into the… Continue reading Self-Assembled Nanostructures Based on Activatable Red Fluorescent Dye for Site-Specific Protein Probing and Conformational Transition Detection
