Leah Pandiscia, PhD
July 28, 2017
This study describes new recombinant water-soluble chlorophyll (Chl)-binding proteins (WSCP) fromLepidium virginicum (LvWSCP). This complex binds four Chls (i.e. two dimers… Continue reading New Insight into the Water-Soluble Chlorophyll-Binding Protein from Lepidium virginicum
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Using duplex DNA–AuNP aggregates, a sequence-specific DNA-binding protein, SQUAMOSA Promoter-binding-Like protein 12 (SPL-12), was directly determined by SPL-12-duplex DNA interaction-based… Continue reading A duplex DNA–gold nanoparticle probe composed as a colorimetric biosensor for sequence-specific DNA-binding proteins
Leah Pandiscia, PhD
July 28, 2017
The formation of G-quadruplex in G-rich regions of DNA can be induced by transcription and is formed within plasmid transcribed… Continue reading Purification of supercoiled G-quadruplex pDNA for in vitrotranscription
Leah Pandiscia, PhD
July 28, 2017
Hydrophobic end-modulated l-phenylalanine-containing triethylene glycol monomethyl ether tagged neutral hydrogelators (1–4) are developed. Investigations determine the gelators’ structure-dependent inclusion of carbon… Continue reading Hydrophobic End-Modulated Amino-Acid-Based Neutral Hydrogelators: Structure-Specific Inclusion of Carbon Nanomaterials
Leah Pandiscia, PhD
July 28, 2017
To achieve an intelligent glucose responsive insulin delivery system with reasonable glucose-sensitivity and minimal long-term side effects, a kind of… Continue reading Well-defined degradable brush-coil block copolymers for intelligent release of insulin at physiological pH
Leah Pandiscia, PhD
July 28, 2017
Nanocarriers incorporating therapeutic and imaging agents within a single nanostructure are emerging tools for drug development and treatment planning. Additional… Continue reading Nanostructure-Dependent Ratiometric NIR Fluorescence Enabled by Ordered Dye Aggregation
Leah Pandiscia, PhD
July 28, 2017
A slower progression of AIDS and increased survival in GBV-C positive individuals, compared with GBV-C negative individuals has been demonstrated;… Continue reading Definition of an 18-mer Synthetic Peptide Derived from the GB virus C E1 Protein as a New HIV-1 Entry Inhibitor
Leah Pandiscia, PhD
July 28, 2017
The Ca2+-binding protein centrin binds to a hydrophobic motif (W1xxL4xxxL8) included in the sequence of several cellular targets: XPC (xeroderma… Continue reading A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin
Leah Pandiscia, PhD
July 28, 2017
Lignin, an abundant terrestrial polymer, is the only large-volume renewable feedstock composed of an aromatic skeleton. Lignin has been used… Continue reading Discovery of 12-mer peptides that bind to wood lignin
Leah Pandiscia, PhD
July 28, 2017
Conformationally constrained peptide has developed as an inhibitor for protein-protein interactions (PPIs), and we have de novo designed cyclized helix-loop-helix (cHLH) peptide… Continue reading Macrocyclization and Labeling of Helix-Loop-Helix peptide with intramolecular bis-thioether linkage
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Macroalgae represents a promising source of fermentable carbohydrates for use in the production of energy efficient biofuel. The primary carbohydrate… Continue reading Engineering broad-spectrum digestion of polyuronides from an exolytic polysaccharide lyase
Leah Pandiscia, PhD
July 28, 2017
Growth and differentiation of the neurites depends on long-distance transport of a specific set of mRNAs to restricted area and… Continue reading TDP-43 binds and transports G-quadruplex-containing mRNAs into neurites for local translation
Leah Pandiscia, PhD
July 28, 2017
Intrinsic disorder is at the center of biochemical regulation and is particularly overrepresented among the often multifunctional viral proteins. Replication… Continue reading Intrinsic Disorder to Order Transitions in the Scaffold Phosphoprotein P from the Respiratory Syncytial Virus RNA Polymerase Complex
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The domain architecture of a large RNA can help explain and/or predict folding, function, biogenesis and evolution. We offer a… Continue reading Ribosomal small subunit domains radiate from a central core
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The role of first-stage β–amyloid aggregation in the development of the Alzheimer disease, is widely accepted but still unclear. Intimate interaction… Continue reading Amyloidβ Peptides in interaction with raft-mime model membranes: a neutron reflectivity insight
Leah Pandiscia, PhD
July 28, 2017