Found 9617 Results / Page 50 of 481
2021 / ChemCioChem
Selective switching of enzymatic activity has been a longstanding goal in synthetic biology. Drastic changes in activity upon mutational manipulation… Continue reading Controlling Enzymatic Activity by Modulating the Oligomerization State via Chemical Rescue and Optical Control
2021 / ChemMedChem
The interaction of metallodrugs with proteins influences their mechanism of action and side effects. In the case of platinum drugs,… Continue reading Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin
2021 / MicrobiologyOpen
In microbial manufacturing, yeast extract is an important component of the growth media. The production of heterologous proteins often varies… Continue reading Machine learning modeling of the effects of media formulated with various yeast extracts on heterologous protein production in Escherichia coli
2021 / Science of Food and Agriculture
Filamentous fungi are the main contamination agent in the viticultural sector. Use of synthetic fungicides is the regular answer to… Continue reading Potential application of lactic acid bacteria in the biopreservation of red grape from mycotoxigenic fungi
2021 / Europen Journal of Neuroscience
Isatin is a biofactor with different biochemical and pharmacological properties whose effects attract much attention because it is an endogenous… Continue reading Participation of glutamatergic and nitrergic systems in the striatal dopamine release induced by isatin, a MAO inhibitor
2021 / Food Science + Technology
In this work, the use of supercritical carbon dioxide, a nontoxic solvent, was proposed to extract bioactive compounds from Juglans… Continue reading Recovery of bioactive compounds from walnut (Juglans regia L.) green husk by supercritical carbon dioxide extraction
2021 / ADVANCED SCIENCE
The authors reveal a thermal actuating bilayer that undergoes reversible deformation in response to low-energy thermal stimuli, for example, a… Continue reading Directional, Low-Energy Driven Thermal Actuating Bilayer Enabled by Coordinated Submolecular Switching
2021 / ANNALS
Salvia clandestina L. is a wild perennial species present in the Salento area of Italy. Here, we examined the in… Continue reading Antitumor and antimigration effects of Salvia clandestina L. extract on osteosarcoma cells
2021 / Chemistry A European Journal
Canonical G-quadruplexes can adopt a variety of different topologies depending on the arrangement of propeller, lateral, or diagonal loops connecting… Continue reading Expanding the Topological Landscape by a G-Column Flip of a Parallel G-Quadruplex
2021 / ChemPhotoChem
Intermolecular Proton Transfer (PT) dynamics can be best studied by optical spectroscopy, which can cover the vast timescale spanned by… Continue reading Solvent-Controlled Intermolecular Proton-Transfer Follows an Irreversible Eigen-Weller Model from fs to ns
2021 / ADVANCED FUNCTIONAL MATERIALS
“Communicating particles” are reported that combine an identification (ID) taggant and a temperature recorder in one single entity—a micron-scaled supraparticle.… Continue reading Communicating Particles: Identification Taggant and Temperature Recorder in One Single Supraparticle
2021 / Engineering in Life Science
Inserting foreign epitopes to hepatitis B core (HBc) virus-like particles (VLPs) could influence the molecular conformation and therefore vary the… Continue reading Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
2021 / Chemistry A European Journal
A family of inherently chiral electroactive selectors based on the 2,2’-biindole atropisomeric scaffold, of easy synthesis and modulable functional properties,… Continue reading Modulating the Enantiodiscrimination Features of Inherently Chiral Selectors by Molecular Design: A HPLC and Voltammetry Study Case with Atropisomeric 2,2’-Biindole-Based Monomers and Oligomer Films
2021 / Microbial biotechnology
The self-sufficient cytochrome P450 RhF and its homologues belonging to the CYP116B subfamily have attracted considerable attention due to the… Continue reading Identification of a self-sufficient cytochrome P450 monooxygenase from Cupriavidus pinatubonensis JMP134 involved in 2-hydroxyphenylacetic acid catabolism, via homogentisate pathway
2021 / PROTEIN SCIENCE
Intrinsically disordered proteins (IDPs) regularly constitute components of larger protein assemblies contributing to architectural stability. Two small, highly acidic IDPs… Continue reading The disordered PCI-binding human proteins CSNAP and DSS1 have diverged in structure and function
2021 / Chemistry A European Journal
The synthesis, structure, magnetic, and photophysical properties of two dinuclear, luminescent, mixed-ligand [CrIII2L(O2CR)]3+ complexes (R=CH3 (1), Ph (2)) of a… Continue reading Synthesis and Characterisation of Luminescent [CrIII2L(μ-carboxylato)]3+ Complexes with High-Spin S=3 Ground States (L=N6S2 donor ligand)
2021 / PROTEIN SCIENCE
Protein stability can be fine-tuned by modifying different structural features such as hydrogen-bond networks, salt bridges, hydrophobic cores, or disulfide… Continue reading A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels
2021 / ChemSusChem
Mechanochemistry is a versatile methodology that can be employed both for covalent bond formation in organic synthesis as well as… Continue reading Mechanochemical Preparation of Protein : hydantoin Hybrids and Their Release Properties
2021 / HELVETICA
The investigation of new synthetic routes towards positively charged N-heterocycles is of high importance for the further development of medicinal… Continue reading Synthesis of Helical and Planar Extended-Phenanthridinium Salts
2021 / Journal of Inherited Hearbolic Disease
Isolated sulfite oxidase deficiency (ISOD) is a rare recessive and infantile lethal metabolic disorder, which is caused by functional loss… Continue reading A defect in molybdenum cofactor binding causes an attenuated form of sulfite oxidase deficiency
