Found 9617 Results / Page 64 of 481
2021 / Nature Communications
Histopathological level imaging in a non-invasive manner is important for clinical diagnosis, which has been a tremendous challenge for current… Continue reading Artificially engineered antiferromagnetic nanoprobes for ultra-sensitive histopathological level magnetic resonance imaging
2021 / Nature Communications
High-entropy alloys (HEAs) have been intensively pursued as potentially advanced materials because of their exceptional properties. However, the facile fabrication… Continue reading Hydrogen spillover-driven synthesis of high-entropy alloy nanoparticles as a robust catalyst for CO2 hydrogenation
2021 / Nature Communications
In living organisms, proteins are organized prevalently through a self-association mechanism to form dimers and oligomers, which often confer new… Continue reading Dimerization and oligomerization of DNA-assembled building blocks for controlled multi-motion in high-order architectures
2021 / Scientific reports
Generally, intermolecular disulfide bond contribute to the conformational protein stability. To identify sites where intermolecular disulfide bond can be introduced… Continue reading A comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab
2021 / Scientific reports
Sequence variants (SV) in protein bio therapeutics can be categorized as unwanted impurities and may raise serious concerns in efficacy… Continue reading Identification, characterization and control of a sequence variant in monoclonal antibody drug product: a case study
2021 / Scientific reports
Over the past few years, biogenic methods for designing silver nanocomposites are in limelight due to their ability to generate… Continue reading Terrestrial snail-mucus mediated green synthesis of silver nanoparticles and in vitro investigations on their antimicrobial and anticancer activities
2021 / Scientific reports
In this investigation, we report the effect on the microscopic dynamics and interactions of the cytokine interferon gamma (IFN-γ) and… Continue reading New insights into the microscopic interactions associated with the physical mechanism of action of highly diluted biologics
2021 / npj 2D Materials and Applications
We report the study of two-dimensional graphitic carbon nitride (GCN) functionalized with copper single atoms as a catalyst for the… Continue reading Copper single-atoms embedded in 2D graphitic carbon nitride for the CO2 reduction
2021 / Scientific reports
Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining… Continue reading A link between pH homeostasis and colistin resistance in bacteria
2021 / Biomolecules
Natural products have been fundamental materials in drug discovery. Traditional strategies for observing natural products with novel structure and/or biological… Continue reading Dilignans with a Chromanol Motif Discovered by Molecular Networking from the Stem Barks of Magnolia obovata and Their Proprotein Convertase Subtilisin/Kexin Type 9 Expression Inhibitory Activity
2021 / Scientific Report
Optically active fullerenes, including C60 and C70 derivatives carrying organic substituents, are used in a range of applications because of… Continue reading Deep-red circularly polarised luminescent C70 derivatives
2021 / Nature Communications
α-Synuclein aggregation is a key driver of neurodegeneration in Parkinson’s disease and related syndromes. Accordingly, obtaining a molecule that targets… Continue reading α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
2021 / Nature Communications
Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Structural… Continue reading Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites
2021 / Nature Communications
A highly efficient, low-cost and environmentally friendly photocathode with long-term stability is the goal of practical solar hydrogen evolution applications.… Continue reading Wittichenite semiconductor of Cu3BiS3 films for efficient hydrogen evolution from solar driven photoelectrochemical water splitting
2021 / Nature Communications
Fluorogenic RNA aptamers are synthetic functional RNAs that specifically bind and activate conditional fluorophores. The Chili RNA aptamer mimics large… Continue reading Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine
2021 / Nature Communications
De novo designed self-assembling peptides (SAPs) are promising building blocks of supramolecular biomaterials, which can fulfill a wide range of… Continue reading Intracellular artificial supramolecules based on de novo designed Y15 peptides
2021 / Nature Communications
Partially unfolded alpha-lactalbumin forms the oleic acid complex HAMLET, with potent tumoricidal activity. Here we define a peptide-based molecular approach… Continue reading Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex
2021 / Scientific Report
Wild ginseng (Panax ginseng) adventitious root cultures were prepared by elicitation using methyl jasmonate and investigated further to find new… Continue reading Curcubinoyl flavonoids from wild ginseng adventitious root cultures
2021 / Nature Communications
Decoding the role of histone posttranslational modifications (PTMs) is key to understand the fundamental process of epigenetic regulation. This is… Continue reading Site-specific ubiquitylation acts as a regulator of linker histone H
2021 / Scientific Report
Unconjugated bilirubin (UCB) is the end-product of heme catabolism in the intravascular compartment. Although beneficial for human health when mildly… Continue reading Physico-chemical characterization of bilirubin-10-sulfonate and comparison of its acid–base behavior with unconjugated bilirubin
