Title
(+)- and (−)-Spongiterpene, a pair of new valerenane sesquiterpene enantiomers from the marine sponge Spongia Sp.
Author
Youg-Qian Liang
Year
2021
Journal
Natural Product Research
Abstract
(+)- and (−)-Spongiterpene [(+)-1 and (−)-1], a pair of new valerenane sesquiterpene enantiomers, along with four known compounds (2-5) were isolated from the marine sponge Spongia sp. The structures of (+)-1 and (−)-1 including absolute configurations were determined by spectroscopic analysis, quantum chemical calculation and X-ray diffraction. Compounds (+)-1 and (−)-1 were the first examples of valerenane sesquiterpenes isolated from the marine sponges. The cytotoxic activities of (+)-1 and (−)-1 were also evaluated.
Instrument
P-2000
Keywords
natural product, enantiomer, structure