Title
Chemical Constituents of Phaius mishmensis
Author
Chen-Wei Jao, Tzu-Heng Hung, Chi-Fen Chang, Ta-Hsien Chuang
Year
2016
Journal
Molecules
Abstract
The partitioned n-hexane, CHCl3, and EtOAc extracts from the crude MeOH extract of Phaius mishmensisshowed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7′R,8′R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods.
Full Article
Instrument
J-715
Keywords
Circular dichroism, Stereochemistry, Pharmaceutical