2018 / Science Advances
Bent-core liquid crystal (LC) molecules are known to form mesophases with fascinating polar order and supramolecular chirality despite the achiral… Continue reading Phase behaviors of colloidal analogs of bent-core liquid crystals
2019 / Journal of Medicinal Chemistry
RE31 is a 31-nt DNA aptamer, consisting of the G quadruplex and a duplex domain, which is able to effectively… Continue reading Improved RE31 analogues containing modified nucleic acid monomers: thermodynamic, structural and biological effects
2019 / Luminescence
Maltol, a food additive, is extensively used in our daily life. To date, its biological safety is still debated. In… Continue reading Spectroscopic characterization, calorimetric study and molecular docking to evaluate the bioconjugation of maltol with hemoglobin
2019 / Journal of Molecular Biology
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTD) are incurable motor neuron diseases associated with muscle weakness, paralysis and… Continue reading RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43
2019 / Polymers
: Newly synthesized two kinds of achiral phenylacetylenes having a free-base- or a zinc-porphyrin (1 and Zn1, respectively) were polymerized by using a… Continue reading Helix-Sense-Selective Polymerization of Phenylacetylenes Having a Porphyrin and a Zinc-Porphyrin Group: One-Handed Helical Arrangement of Porphyrin Pendants
2019 / Langmuir
Chiral nanostructures exhibited distinctive functions and attractive application in complex biological systems, which demonstrated the subject of many outstanding researches.… Continue reading Chiral Nanostructured Composite Films via Solvent-Tuned Self-Assembly and Their Enantioselective Performances
2019 / Scientific Reports
Der p 2 is a major dust mite allergen and >80% of mite allergic individuals have specifc IgE to this… Continue reading The major allergen Der p 2 is a cholesterol binding protein
2019 / ChemBioChem
Antimicrobial peptides (AMPs) kill bacteria by targeting their membranes via various mechanisms involving peptide assembly often coupled with disorder‐to‐order structural… Continue reading Manipulating Active Structure and Function of Cationic Antimicrobial Peptide CM15 by the Polysulfonated Drug Suramin: A Step Closer to in vivo Complexity
2018 / Scientific Reports
Bromo-Noscapine (BrNs) is a tubulin-binding cytotoxic agent with significant activity against breast and lung cancer. The mechanistic interaction insight into… Continue reading Mechanistic Interaction Study of Bromo-Noscapine with Bovine Serum Albumin employing Spectroscopic and Chemoinformatics Approaches
2018 / Inorganic Chemistry
Zinc ion binding is a principal event in the achievement of the correct fold in classical zinc finger domains since… Continue reading Ni(II), Hg(II), and Pb(II) Coordination in the Prokaryotic Zinc-Finger Ros87
2018 / Bioorganic & Medicinal Chemistry
Two new sesquiterpene-based analogues, namely harzianoic acids A (1) and B (2), were isolated from a sponge-associated fungus Trichoderma harzianum. Their… Continue reading Harzianoic acids A and B, new natural scaffolds with inhibitory effects against hepatitis C virus
2018 / Journal of Natural Products
Five new water-soluble amido- and aminoanthraquinone pigments, hypalocrinins A–E (1–5), the new amidoanthraquinone biaryls hypalocrinin F (6) and hypalocrinin G… Continue reading Hypalocrinins, Taurine-Conjugated Anthraquinone and Biaryl Pigments from the Deep Sea Crinoid Hypalocrinus naresianus
2019 / antioxidants
Members of the DJ-1 protein family are multifunctional enzymes whose loss increases the susceptibility of the cell to oxidative stress.… Continue reading Bifunctional Chloroplastic DJ-1B from Arabidopsis thaliana is an Oxidation-Robust Holdase and a Glyoxalase Sensitive to H2O2
2018 / ACS Omega
In this paper, we present a new synthetic route to produce optically active nanofibers of poly[2-(sec-butyl) aniline] (PSBA). Optically active… Continue reading Optically Active Poly[2-(sec-butyl)aniline] Nanofibers Prepared via Enantioselective Polymerization
2018 / Journal of Biological Chemistry
Small heat-shock proteins (sHsps) are ubiquitous molecular chaperones, and sHsp mutations or altered expression are linked to multiple human disease… Continue reading It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate
2018 / The Journal of Physical Chemistry B
Vibrational circular dichroism (CD) and IR spectra of dichloromethane solutions of l-stercobilin and d-urobilin hydrochlorides have been recorded in the mid-IR region.… Continue reading l-Stercobilin-HCl and d-Urobilin-HCl. Analysis of Their Chiroptical and Conformational Properties by VCD, ECD, and CPL Experiments and MD and DFT Calculations
2019 / International Immunopharmacology
The oral route is one of the most convenient routes for drug and/or vaccine delivery. Yet variable nature of gastrointestinal tract due… Continue reading Chylomicron mimicking solid lipid nanoemulsions encapsulated enteric minicapsules targeted to colon for immunization against hepatitis B
2018 / CrystEngComm
The self-assembly of N- and C-protected tripeptides, Boc-Gly-Phe-Phe-OMe (1) and its analog Boc-Gly-Phg-Phe-OMe (2, Phg = phenylglycine), has been investigated.… Continue reading Unique crystallographic signatures of Boc-Gly-Phe-Phe-OMe and Boc-Gly-Phg-Phe-OMe and their self-association
2018 / International Journal of Molecular Sciences
SOUL, a heme-binding protein-2 (HEBP-2), interacts with apoptosis-linked gene 2 protein (ALG-2) in a Ca2+-dependent manner. To investigate the properties… Continue reading Thermodynamic Characterization of the Ca2+-Dependent Interaction Between SOUL and ALG-2
2018 / JACS
The synthesis of chiral polyoxometalates (POMs) is a challenge because of the difficulty to induce the formation of intrin-sically chiral… Continue reading Stereoselective Assembly of Gigantic Chiral Molybdenum Blue Wheels Using Lanthanide ions and Amino Acids
