2021 / Scientific Reports
Helicobacter pylori is a Gram-negative bacterium that causes chronic inflammations in the stomach area and is involved in ulcers, which… Continue reading Biophysical characterization of the homodimers of HomA and HomB, outer membrane proteins of Helicobacter pylori
2022 / Scientific Reports
Venezuelan equine encephalitis virus (VEEV) is a mosquito borne alphavirus which leads to high viremia in equines followed by lethal… Continue reading Bivalent single domain antibody constructs for effective neutralization of Venezuelan equine encephalitis
2022 / Scientific Reports
Protease inhibitors (PIs) are important biotechnological tools of interest in agriculture. Usually they are the first proteins to be activated… Continue reading TcTI, a Kunitz-type trypsin inhibitor from cocoa associated with defense against pathogens
2021 / Scientific Reports
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in humans, affecting ~ 500 million worldwide. A detailed study of the structural… Continue reading Combined effects of double mutations on catalytic activity and structural stability contribute to clinical manifestations of glucose-6-phosphate dehydrogenase deficiency
2022 / Scientific Reports
Owing to its great threat to human health and environment, Pb2+ pollution has been recognized as a major public problem… Continue reading Structure-guided development of Pb2+-binding DNA aptamers
2022 / Scientific Reports
Membrane environment often has an important effect on the structure, and therefore also on the coordination mode of biologically relevant… Continue reading Thermodynamic surprises of Cu(II)–amylin analogue complexes in membrane mimicking solutions
2021 / Chemistry A European Journal
Human telomeric DNA with hundreds of repeats of the 5’-TTAGGG-3’ motif plays a crucial role in several biological processes. It… Continue reading The Binding Pocket at the Interface of Multimeric Telomere G-quadruplexes: Myth or Reality?
2021 / ADVANCED SCIENCE
Recently, viral infectious diseases, including COVID-19 and Influenza, are the subjects of major concerns worldwide. One strategy for addressing these… Continue reading Hemagglutinin Nanoparticulate Vaccine with Controlled Photochemical Immunomodulation for Pathogenic Influenza-Specific Immunity
2021 / ADVANCED HEALTHCARE MATERIALS
Uncontrolled amyloid-beta (Aβ) fibrillation leads to the deposition of neurotoxic amyloid plaques and is associated with Alzheimer’s disease. Inhibiting Aβ… Continue reading Reversing Aβ Fibrillation and Inhibiting Aβ Primary Neuronal Cell Toxicity Using Amphiphilic Polyphenylene Dendrons
2021 / FEBS Journal
The incidence of metastatic breast cancer (MBC) is increasing and the therapeutic arsenal available to fight it is insufficient. Brain… Continue reading The antimetastatic breast cancer activity of the viral protein-derived peptide vCPP2319 as revealed by cellular biomechanics
2021 / MicorobiologyOpen
Temperate phages are bacterial viruses that after infection either reside integrated into a bacterial genome as prophages forming lysogens or… Continue reading Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans
2021 / Tlanslational Psychiatry
Chronic mental illnesses (CMIs) pose a significant challenge to global health due to their complex and poorly understood etiologies and… Continue reading Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses
2021 / Food Science & Nutrition
In order to elucidate the substantial effect and underlying mechanism of endogenous collagen on the texture development of fish balls,… Continue reading Heat-induced structural changes in fish muscle collagen related to texture development in fish balls: Using eel ball as a study model
2021 / FEBS Journal
Human transferrin receptor 1 (TfR) is necessary for the delivery of the iron carrier protein transferrin into cells and can… Continue reading Motif-driven protein binder design towards transferrin receptor helical domain
2021 / Microbial biotechnology
Secreted proteins and peptides hold large potential both as therapeutics and as enzyme catalysts in biotechnology. The high stability of… Continue reading DisCoTune: versatile auxiliary plasmids for the production of disulphide-containing proteins and peptides in the E. coli T7 system
2021 / EurJOC
We report new stromatal azaphilone pigments rubiginosins Z-X from the ascomycete Hypoxylon rubiginosum, as well as rubiginosins Z and W… Continue reading Azaphilone Pigments from Hypoxylon rubiginosum and H. texense: Absolute Configuration, Bioactivity, and Biosynthesis
2021 / ADVANCED OPTICAL MATERIALS
Gold nanoclusters (AuNCs) are nanomaterials with interesting photoluminescent properties that can be endowed with biomolecular recognition and biocompatibility when stabilized… Continue reading Tuning the Optical Properties of Au Nanoclusters by Designed Proteins
2021 / ADVANCED NANOBIOMED RESEARCH
Organ fabrication as the solution to renewable donor demands requires the ability to spatially deposit viable cells into biologically relevant… Continue reading Hybrid Self-Assembling Peptide/Gelatin Methacrylate (GelMA) Bioink Blend for Improved Bioprintability and Primary Myoblast Response
2021 / ADVANCED FUNCTIONAL MATERIALS
A general and versatile technology to engineer light-responsive protein-based biomaterials can enable the manipulation and interrogation of proteins, pathways, and… Continue reading Genetically Encoding Light-Responsive Protein-Polymers Using Translation Machinery for the Multi-Site Incorporation of Photo-Switchable Unnatural Amino Acids
2021 / Aging Cell
Frontotemporal dementia and amyotrophic lateral sclerosis are fatal and incurable neurodegenerative diseases linked to the pathological aggregation of the TDP-43… Continue reading New lessons on TDP-43 from old N. furzeri killifish
