Racemic mixtures of aminomethylenehelicene (P)- and (M)-pentamers exhibited deterministic and stochastic chiral symmetry breaking during hetero-double-helix formation and self-assembly in… Continue reading Deterministic and Stochastic Chiral Symmetry Breaking Exhibited by Racemic Aminomethylenehelicene Oligomers
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Energy coupling factor (ECF) transporters are responsible for the uptake of essential scarce nutrients in prokaryotes. This ATP-binding cassette transporter… Continue reading Crystal Structure of a Group I Energy Coupling Factor Vitamin Transporter S Component in Complex with Its Cognate Substrate
Leah Pandiscia, PhD
July 28, 2017
Zinc finger proteins are associated with hereditary diseases and cancers. To obtain an adequate amount of zinc finger proteins for… Continue reading Effect of His-Tag on Expression, Purification, and Structure of Zinc Finger Protein, ZNF191(243-368)
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A,D-substituted cyclodextrin (CDX) substituted on their primary rim side are ideal scaffolds for the macromolecular assembly and formation of templated… Continue reading On the synthesis of cyclodextrin–peptide conjugates by the Huisgen reaction
Leah Pandiscia, PhD
July 28, 2017
A new lignan glycoside, 1-[3,6-(4,4′-dihydroxy-3,3′-dimethoxy-δ-truxinyl)-β-fructofuranosyl]-α-glucopyranoside (1), named coixlachryside A, together with nine known simple phenolic compounds (3–11) were isolated from… Continue reading Coixlachryside A: A new lignan glycoside from the roots of Coix lachryma-jobi L. var. ma-yuen Stapf.
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Intracellular α-synuclein deposits, known as Lewy bodies, have been linked to a range of neurodegenerative disorders, including Parkinson’s disease. α-Synuclein… Continue reading Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
Leah Pandiscia, PhD
July 28, 2017
The interactions between nanoparticles and proteins have prime importance in nanomedicine and nanotoxicology. L-Cysteine capped copper sulfide (Cy-CuS) nanoparticles having average… Continue reading Exploring the interaction of L-cysteine capped CuS nanoparticles with bovine serum albumin (BSA): a spectroscopic study
Leah Pandiscia, PhD
July 28, 2017
Interaction between bovine serum albumin (BSA) and phosphorus heterocycles (PHs) was studied using multi-spectroscopic techniques. The results indicated the high… Continue reading Binding interaction of phosphorus heterocycles with bovine serum albumin: A biochemical study
Leah Pandiscia, PhD
July 28, 2017
Reactive oxygen species, the byproducts of oxygenases reaction, when in excess, promote degenerative diseases like cardiovascular, cancer and arthritis. Sesame… Continue reading Inhibition of lipoxygenase by sesamol corroborates its potential anti-inflammatory activity
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Clavanins is a class of peptides (23aa) histidine-rich, free of post-translational modifications. Clavanins have been studied largely for their ability… Continue reading Structural Studies of a Lipid-Binding Peptide from Tunicate Hemocytes with Anti-Biofilm Activity
Leah Pandiscia, PhD
July 28, 2017
The long terminal repeat (LTR) of the proviral human immunodeficiency virus (HIV)-1 genome is integral to virus transcription and host… Continue reading Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Poly(vinylamine-co-N-vinylisobutylamide) or poly(VAm-co-NVIBA) was evaluated for its ability to stabilize double-stranded DNA (dsDNA) with the controlled formation or dissociation of… Continue reading Controlled DNA interpolyelectrolyte complex formation or dissociation via stimuli-responsive poly(vinylamine-co-N-vinylisobutylamide)
Leah Pandiscia, PhD
July 28, 2017