2016 / Journal of Food
In this study, two horseradish peroxidase (HRP)-based modifications were used to treat whey protein isolate (WPI) and skim milk powder… Continue reading Two horseradish peroxidase-based modifications result in two milk protein products with ordered secondary structure and enhanced in vitro antigenicity
2016 / Extremophiles
Biosynthesis of L-tyrosine (L-Tyr) and L-phenylalanine (L-Phe) is directed by the interplay of three enzymes. Chorismate mutase (CM) catalyzes the… Continue reading Characterization of two key enzymes for aromatic amino acid biosynthesis in symbiotic archaea
2016 / Journal of Biological Inorganic Chemistry
Both Met104 and Met105 are involved, either directly or indirectly, in the redox mediated ligand switch of the heme-dependent transcription factor, RcoM-1.… Continue reading Met104 is the CO-replaceable ligand at Fe(II) heme in the CO-sensing transcription factor BxRcoM-1
2016 / Biopolymers
Regulatory regions in the genome can act through a variety of mechanisms that range from the occurrence of histone modifications… Continue reading Evidence for a quadruplex structure in the polymorphic hs1.2 enhancer of the immunoglobulin heavy chain 3′ Regulatory Regions and its conservation in mammals
2016 / Journal of Photochemistry and Photobiology B: Biology
Carbon nanotubes (CNTs) with unique and outstanding properties were expected to revolutionize various aspects of the biomedical sector. Interaction studies… Continue reading Prion like behavior of HSA-hydroxylated MWCNT interface
2016 / Peptide Science
The transcription factor p53 has a tumor suppressor role in leading damaged cells to apoptosis. Its activity is regulated/inhibited in… Continue reading Development of cell-penetrating peptide-based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions
2016 / RSC Advances
A combination of circular dichroism, steady-state and time-resolved fluorescence, and low temperature phosphorescence spectroscopy has been used to study guanidine… Continue reading Stepwise unfolding of a multi-tryptophan protein MPT63 with immunoglobulin-like fold: detection of zone-wise perturbation during guanidine hydrochloride-induced unfolding using phosphorescence spectroscopy
2016 / Soft Matter
A human telomere DNA segment (HT-DNA) can fold into a G-quadruplex in the presence of some monovalent cations. These cations… Continue reading The effects of monovalent metal ions on the conformation of human telomere DNA using analytical ultracentrifugation
2016 / Peptide Science
Holins are pore-forming membrane proteins synthesized by lytic phages. The second transmembrane domain (TM2) of Mycobacteriophage D29 holin presents an… Continue reading Solvation Driven Conformational Transitions in the Second Transmembrane Domain of Mycobacteriophage Holin
2016 / Metallomics
The sole role of bradykinin (BK) as an inflammatory mediator is controversial, as recent data also support an anti-inflammatory role… Continue reading Copper, differently from zinc, affects the conformation, oligomerization state and activity of bradykinin
2016 / Food & Function
Bovine α-lactalbumin (α-La) is a major food allergen found in milk and is characterized by high conformational stability because of… Continue reading Potential allergenicity response to structural modification of irradiated bovine α-lactalbumin
2016 / Journal of Asian Natural Products Research
Phytochemical investigation on the whole plants of Iris japonica led to the isolation of four new aromatic glycosides. Their structures including the… Continue reading Aromatic glycosides from the whole plants ofIris japonica
2016 / Journal of Asian Natural Products Research
Three new lignanosides (+)-(8S,7′S,8′S)-burselignan-9′-O-β-d-glucopyrano side (1), (+)-(8R,7′S,8′R)-isolariciresinol-9′-O-β-d-fucopyranoside (2), (-)-(8S, 7′R,8′R)-methoxyisoariciresinol-9′-O-α-l-rhamnoside (3), along with four known compounds, were isolated from the… Continue reading Three new lignanosides from the aerial parts of Lespedeza cuneata
2016 / Green Chemistry
We explored the production of hydrazine from NO and ammonium by anammox biomass, which normally converts ammonium and nitrite to… Continue reading Hydrazine production by anammox biomass with NO reversible inhibition effects
2016 / PLoS ONE
The C-terminal region of the M-protein of Streptococcus pyogenes is a major target for vaccine development. The major feature is the C-repeat… Continue reading Predicted Coverage and Immuno-Safety of a Recombinant C-Repeat Region Based Streptococcus pyogenes Vaccine Candidate
2016 / Applied Materials and Interfaces
Silk is useful as a drug carrier due to its biocompatibility, tunable degradation, and outstanding capacity in maintaining the function… Continue reading Injectable and pH-Responsive Silk Nanofiber Hydrogels for Sustained Anticancer Drug Delivery
2016 / RSC Advances
Chiral carbon quantum dots (L-carbon quantum dots, L-CQDs; and D-carbon quantum dots, D-CQDs) were synthesized through the facile hydrothermal treatment of carbonated citric… Continue reading One-step synthesis of chiral carbon quantum dots and their enantioselective recognition
2016 / Proteins
The pathogenic bacteria Legionella pneumophila is known to cause Legionnaires’ Disease, a severe pneumonia that can be fatal to immunocompromised individuals and… Continue reading Characterization of the structure and catalytic activity of Legionella pneumophila VipF
2016 / Journal of Food Processing and Preservation
The effects of processing (dry-milling, cooking, isoelectric precipitation) on the physicochemical, functional and nutritional properties of lentil were evaluated. Protein,… Continue reading Comparative Study of the Effects of Processing on the Nutritional, Physicochemical and Functional Properties of Lentil
2016 / Scientific Reports
Trimeric autotransporter adhesins (TAAs), cell surface proteins of Gram-negative bacteria, mediate bacterial adhesion to host cells and extracellular matrix proteins.… Continue reading An Acinetobacter trimeric autotransporter adhesin reaped from cells exhibits its nonspecific stickiness via a highly stable 3D structure
