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Fed-batch production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in soluble form inEscherichia coli and its purification and characterization

2016 / Protein Expression and Purification

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent. The aim of this study is to produce large… Continue reading Fed-batch production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in soluble form inEscherichia coli and its purification and characterization

Leah Pandiscia, PhD July 28, 2017

6,8-Di-C-methyl-flavonoids with neuroprotective activities fromRhododendron fortunei

2016 / Fitoterapia

Six 6,8-di-C-methyl-flavonoids, (2R,3R)-6,8-di-C-methyl-5,7,4′-trihydroxyflavanonol 7-O-β-d-gluco-pyranoside (1), (2R,3R)-6,8-di-C-methyl-5,7,4′-trihydroxyflavanonol 7-O-β-d-xylopyranosyl(1 → 6)-β-d-glucopyranoside (2), 6,8-di-C-methylkaempferol 7-O-β-d-glucopyranoside (3), (2R)-farrerol (4a), (2R/2S)-farrerol 7-O-β-d-glucopyranoside (5), and (2R/2S)-farrerol 7-O-β-d-xylopyranosyl(1 → 6)-β-d-glucopyranoside (6),… Continue reading 6,8-Di-C-methyl-flavonoids with neuroprotective activities fromRhododendron fortunei

Leah Pandiscia, PhD July 28, 2017

Optically Active Helical Polyacetylene Bearing Ferrocenyl Amino-Acid Derivative in Pendants. Preparation and Application as Chiral Organocatalyst for Asymmetric Aldol Reaction

2016 / Industrial & Engineering Chemical Research

The article reports a novel type of helical polymer-based chiral catalyst for catalyzing asymmetric aldol reactions. Chiral acetylenic monomers containing… Continue reading Optically Active Helical Polyacetylene Bearing Ferrocenyl Amino-Acid Derivative in Pendants. Preparation and Application as Chiral Organocatalyst for Asymmetric Aldol Reaction

Leah Pandiscia, PhD July 28, 2017

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

2016 / Emerging Microbes & Infections

After three decades of intensive research efforts, an effective vaccine against HIV-1 remains to be developed. Several broadly neutralizing antibodies… Continue reading An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

Leah Pandiscia, PhD July 28, 2017

Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates

2016 / Journal of Photochemistry and Photobiology B: Biology

Triarylmethane derivatives are extensively investigated as antitumor and antibacterial drug candidates alone and as photoactivatable compounds. In the series of… Continue reading Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates

Leah Pandiscia, PhD July 28, 2017

Coixlachryside A: A new lignan glycoside from the roots ofCoix lachryma-jobi L. var. ma-yuen Stapf.

2016 / Phytochemistry Letters

A new lignan glycoside, 1-[3,6-(4,4′-dihydroxy-3,3′-dimethoxy-δ-truxinyl)-β-fructofuranosyl]-α-glucopyranoside (1), named coixlachryside A, together with nine known simple phenolic compounds (3–11) were isolated from… Continue reading Coixlachryside A: A new lignan glycoside from the roots ofCoix lachryma-jobi L. var. ma-yuen Stapf.

Leah Pandiscia, PhD July 28, 2017

Changes in fluorescent dissolved organic matter upon interaction with anionic surfactant as revealed by EEM-PARAFAC and two dimensional correlation spectroscopy

2016 / Chemosphere

Surfactants are present in significant amounts in both domestic and industrial wastewater, which may interact with dissolved organic matter (DOM).… Continue reading Changes in fluorescent dissolved organic matter upon interaction with anionic surfactant as revealed by EEM-PARAFAC and two dimensional correlation spectroscopy

Leah Pandiscia, PhD July 28, 2017