2016 / Biochemistry
Ultrasonication is considered one of the most effective agitations for inducing the spontaneous formation of amyloid fibrils. When we induced… Continue reading Thioflavin T-Silent Denaturation Intermediates Support the Main-Chain-Dominated Architecture of Amyloid Fibrils
2016 / Physical Chemistry Chemical Physics
Remarkably little is known about the mechanism of action of ice nucleation proteins (INPs), although their ability to trigger ice… Continue reading Ice nucleation of an insect lipoprotein ice nucleator (LPIN) correlates with retardation of the hydrogen bond dynamics at the myo-inositol ring
2016 / Scientific Reports
The photochromic properties of azobenzene, involving conformational changes occurring upon interaction with light, provide an excellent tool to establish new… Continue reading Photochromic switching of the DNA helicity induced by azobenzene derivatives
2016 / The FEBS Journal
Antimicrobial-resistant and hospital-adapted Enterococcus faecium represents a clinical problem in immunocompromised patients in hospitals worldwide. Understanding the molecular pathogenesis ofE. faecium infections may… Continue reading The crystal structure of the ligand-binding region of serine-glutamate repeat containing protein A (SgrA) of Enterococcus faecium reveals a new protein fold: functional characterization and insights into its adhesion function
2016 / Biophysical Chemistry
The conversion of proteins into amyloid fibrils and other amyloid-like aggregates is closely connected to the onset of a series… Continue reading Trifluoroethanol modulates α-synuclein amyloid-like aggregate formation, stability and dissolution
2016 / PLoS ONE
MNEI is a single chain derivative of monellin, a plant protein that can interact with the human sweet taste receptor,… Continue reading Molecular Dynamics Driven Design of pH-Stabilized Mutants of MNEI, a Sweet Protein
2004 / Journal of Polymer Science Part A: Polymer Chemistry
A series of optically active dendrons with a primary amino group at the terminal were prepared fromL- or D-glutamic acid, and… Continue reading Helicity induction on a poly(phenylacetylene) bearing a phosphonate residue by chiral dendrons
2001 / Chemical and Pharmaceutical Bulletin
Two new pyrrolidine alkaloids, radicamines A and B were isolated as inhibitors of α-glucosidase from Lobelia chinensis LOUR. (Campanulaceae). Radicamines… Continue reading Two New Pyrrolidine Alkaloids, Radicamines A and B, as Inhibitors of α-Glucosidase from Lobelia chinensis LOUR
2016 / Applied Microbiology and Biotechnology
Human interleukin-7 (hIL-7) is a therapeutically important cytokine involved in lymphocyte development and survival. In previous reports, a uniformly poor… Continue reading A combinatorial approach of N-terminus blocking and codon optimization strategies to enhance the soluble expression of recombinant hIL-7 in E. colifed-batch culture
2016 / Journal of Colloid and Interface Science
The activating role of different polymer thin films coated over polystyrene support on theSynechococcus sp. biofilm growth was examined concurrently by… Continue reading Thin films of silk fibroin and its blend with chitosan strongly promote biofilm growth of Synechococcus sp. BDU 140432
2016 / Biochemical and Biophysical Research Communications
In Alzheimer’s disease, soluble Aβ oligomers are believed to play important roles in the disease pathogenesis, and their levels correlate… Continue reading Structural differences between amyloid beta oligomers
2016 / Journal of Biological Inorganic Chemistry
Contributions of the active site metal to the stability of carbonic anhydrase (CA) were quantified by differential scanning calorimetry and… Continue reading Coordination contributions to protein stability in metal-substituted carbonic anhydrase
2016 / International Journal of Biological Macromolecules
The mce4A gene of Mycobacterium tuberculosis encodes a 400 amino acid residues protein of 43 kDa, which is a mammalian cell entry protein (Mce4A) and… Continue reading Purification and Structural Characterization of Mce4A fromMycobacterium tuberculosis
2016 / Colloids and Surfaces B: Biointerfaces
Here, we demonstrated that starch-capped silver nanoparticles (AgNPST) with a size range of 10–15 nm could readily interact with a small… Continue reading Protein corona over silver nanoparticles triggers conformational change of proteins and drop in bactericidal potential of nanoparticles: Polyethylene glycol capping as preventive strategy
2016 / Process Biochemistry
This study reports a thermostable Cu, Zn superoxide dismutase (SOD) obtained from a high-altitude plant Caragana jubata (Cj-Cu, Zn SOD). The expression… Continue reading Copper, zinc superoxide dismutase from Caragana jubata: A thermostable enzyme that functions under a broad pH and temperature window
2016 / International Journal of Biological Macromolecules
Carbonic anhydrase VA (CAVA) is a mitochondrial enzyme belonging to the α-family of CAs, which is involved in several physiological… Continue reading GdnHCl-induced unfolding intermediate in the mitochondrial carbonic anhydrase VA
2016 / Colloids and Surfaces B: Biointerfaces
The interaction of natural lipopeptide pseudofactin II with a series of doubly charged metal cations was examined by matrix–assisted laser–desorption… Continue reading Structure and mode of action of cyclic lipopeptide pseudofactin II with divalent metal ions
2016 / Photochemistry and Photobiology
Replacement of some hydrophobic solvent-exposed residues in Lampyris turkestanicus luciferase with arginine increases thermostability of this enzyme. Herein, thermodynamic and kinetic of… Continue reading Surface Arginine Saturation Effect on Unfolding Reaction of Firefly Luciferase: A Thermodynamic and Kinetic Perspective
2016 / International Journal of Pharmaceutics
We present here an approach to non-covalently combine an engineered model protein with a PEGylated peptide via coiled-coil binding. To… Continue reading Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology
2016 / Journal of Photochemistry and Photobiology B: Biology
The interaction of Rhodamine B (RB) with Lysozyme (Lys) was investigated by different optical spectroscopic techniques such as absorption, fluorescence,… Continue reading Interaction of Lysozyme with Rhodamine B: A combined analysis of spectroscopic & molecular docking
