Carbon dots (CDs) have been widely used as candidates for drug carriers and bio-imaging probes because of their high drug… Continue reading The effects of a series of carbon dots on fibrillation and cytotoxicity of human islet amyloid polypeptide
Leah Pandiscia, PhD
July 28, 2017
The ground- and excited-state interactions of Pt(II) meso-tetrakis(4-N-methylpyridyl)porphyrin (PtTMPyP4) with polynucleotides [poly(dG-dC)]2 and [poly(dA-dT)]2 have been investigated using UV/visible, circular dichroism, and steady-state… Continue reading Ground and excited state interactions of metalloporphyrin PtTMPyP4 with polynucleotides [poly(dG-dC)]2 and [poly(dA-dT)]2
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Two major complexes form structural bridges that connect the erythrocyte membrane to its underlying spectrin-based cytoskeleton. Although the band 3-ankyrin… Continue reading Identification of Adducin-Binding Residues on the Cytoplasmic Domain of Erythrocyte Membrane Protein, Band 3
Leah Pandiscia, PhD
July 28, 2017
Human immunodeficiency virus (HIV) infection and the progression to AIDS are characterized by the depletion of CD4+ T-cells. HIV-1 infection leads… Continue reading The Glutamine-rich Region of the HIV-1 Tat Protein Is Involved in T-cell Apoptosis
Leah Pandiscia, PhD
July 28, 2017
Knowledge of the structural properties of linker histones is important to the understanding of their role in higher-order chromatin structure… Continue reading An inducible helix–Gly–Gly–helix motif in the N-terminal domain of histone H1e: A CD and NMR study
Leah Pandiscia, PhD
July 28, 2017
The binding mode of porphyrins, namely meso-tetrakis(N-methyl pyridinium-4-yl)porphyrin (H2TMPyP), was classified in this work by absorption and circular dichroism(CD) spectroscopy. The… Continue reading Classification of CD and absorption spectra in the Soret band of H2TMPyP bound to various synthetic polynucleotides
Leah Pandiscia, PhD
July 28, 2017
The utilisation of chiral penicillamine stabilisers allowed the preparation of new water soluble white emitting CdS nano-tetrapods, which demonstrated circular dichroism in the band-edge… Continue reading Chiral luminescent CdS nano-tetrapods
Leah Pandiscia, PhD
July 28, 2017
In type 2 diabetes mellitus (T2DM), misfolded human islet amyloid polypeptide (hIAPP) forms amyloid deposits in pancreatic islets. These amyloid… Continue reading Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide
Leah Pandiscia, PhD
July 28, 2017
This paper describes an electrochemical biosensor for free cholesterol monitoring. The sensor is a multienzymatic electrodic system in which horseradish… Continue reading An electrochemical multienzymatic biosensor for determination of cholesterol
Leah Pandiscia, PhD
July 28, 2017
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as… Continue reading Synthesis and capping of water-dispersed gold nanoparticles by an amino acid: Bioconjugation and binding studies
Leah Pandiscia, PhD
July 28, 2017
Purified native silk fibroin forms β-sheet-rich, physically cross-linked, hydrogels from aqueous solution, in a process influenced by environmental parameters. Previously we… Continue reading Sonication-induced gelation of silk fibroin for cell encapsulation
Leah Pandiscia, PhD
July 28, 2017
Polymerization of the amyloid β-peptide (Aβ) has been identified as a major feature of the pathogenesis of Alzheimer’s disease (AD).… Continue reading NMR and CD studies on the interaction of Alzheimer β-amyloid peptide (12–28) with β-cyclodextrin
Leah Pandiscia, PhD
July 28, 2017
The effect of milk on the antioxidant capacity of tea polyphenols is not fully understood. The complexation of tea polyphenols… Continue reading Milk β-lactoglobulin complexes with tea polyphenols
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Methanobactin (mb) is a novel chromopeptide that appears to function as the extracellular component of a copper acquisition system in… Continue reading Spectral and thermodynamic properties of Ag(I), Au(III), Cd(II), Co(II), Fe(III), Hg(II), Mn(II), Ni(II), Pb(II), U(IV), and Zn(II) binding by methanobactin from Methylosinus trichosporiumOB3b
Leah Pandiscia, PhD
July 28, 2017
To elucidate the effect of gamma-irradiation on the molecular properties of ovalbumin and ovomucoid, the secondary and tertiary structure and… Continue reading Effect of γ-irradiation on the molecular properties of ovalbumin and ovomucoid and protection by ascorbic acid
Leah Pandiscia, PhD
July 28, 2017
The effects of ions (i.e. Na+, Mg2+ and polyamines including spermidine and spermine) on the stability of various DNA oligonucleotides in… Continue reading Effects of polyamines on the thermal stability and formation kinetics of DNA duplexes with abnormal structure
Leah Pandiscia, PhD
July 28, 2017
Tylophorine B exhibits 60% inhibition against tobacco mosaic virus (TMV) at a concentration of 1.0 × 10−6 g/ml. In our study, high affinity… Continue reading The interaction between tylophorine B and TMV RNA
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017