2007 / Biophysical Chemistry
We here report an experimental study on the thermal aggregation process of concanavalin A, a protein belonging to the legume… Continue reading Amyloid fibrils formation and amorphous aggregation in concanavalin A
2007 / European Journal of Medicinal Chemistry
The DNA binding properties of three cation-substituted anthrapyrazole derivatives of emodin with calf thymus DNA were characterized by spectroscopic methods… Continue reading Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin
2001 / Tetrahedron
The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluorescence sensor for chiral amines and amino alcohols. The fluorescence of HELIXOL… Continue reading 2,15-Dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor
2008 / The Journal of Biological Chemistry
The question of whether distinct self-propagating structures could be formed within the same amino acid sequence in the absence of… Continue reading The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States
2000 / PNAS
Filamentous inclusions made of a-synuclein constitute the defining neuropathological characteristic of Parkinson’s disease, dementia with Lewy bodies, and multiple system… Continue reading Fiber diffraction of synthetic a-synuclein filaments shows amyloid-like cross-b conformation
2006 / Journal of Agricultural and Food Chemistry
Four new quercetin-derived oxidation products (1-4) and lunularin-4-O-â-D-glucoside (5) were isolated from a water extract of onion (Allium cepa) skin,… Continue reading Antibacterial and Antioxidant Activities of Quercetin Oxidation Products from Yellow Onion (Allium cepa) Skin
2006 / The Journal of Biological Chemistry
The intracellular deposition of fibrillar aggregates of α-synuclein is a characteristic feature of Parkinson disease. Alternatively, as a result of… Continue reading Binding of α-Synuclein Affects the Lipid Packing in Bilayers of Small Vesicles
2006 / Journal of Controlled Release
A new approach for attaining sustained release of protein is introduced, involving a pore-closing process of preformed porous PLGA microspheres.… Continue reading Biodegradable polymeric microspheres with “open/closed” pores for sustained release of human growth hormone
2008 / Journal of Virology
The tripartite motif (TRIM) protein, TRIM5 , is an endogenous factor in primates that recognizes the capsids of certain retroviruses… Continue reading Biochemical and Biophysical Characterization of a Chimeric TRIM21-TRIM5α Protein
2004 / Biophysical Journal
Linear dichroism (LD) can be used to study the alignment of absorbing chromophores within long molecules. In particular, Couette flow… Continue reading Micro-Volume Couette Flow Sample Orientation for Absorbance and Fluorescence Linear Dichroism
2005 / Biochemical and Biophysical Research Communications
Death receptors (DRs) can induce apoptosis by oligomerization with TRAIL, whereas death decoy receptors (DcRs) cannot, due to their lack… Continue reading Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors
2008 / The Journal of Biological Chemistry
Rabbit liver cytochrome P450 (P450) 1A2 was found to catalyze the 5,6-epoxidation of α-naphthoflavone (αNF), 1-hydroxylation of pyrene, and the… Continue reading Cooperativity in Oxidation Reactions Catalyzed by Cytochrome P450 1A2 HIGHLY COOPERATIVE PYRENE HYDROXYLATION AND MULTIPHASIC KINETICS OF LIGAND BINDING
2009 / PNAS
Phytochromes are a widespread family of photosensory proteins first discovered in plants, which measure the ratio of red to far-red… Continue reading Distinct classes of red/far-red photochemistry within the phytochrome superfamily
2006 / Phytochemistry
Two eudesmanes, two abietanes, two podocarpanes and other nine known compounds were isolated from the dried fruits of Juniperus polycarpus var. seravschanica. Their… Continue reading Terpenoids from Juniperus polycarpus var. seravschanica
2013 / Journal of Experimental Botany
2-Cysteine peroxiredoxins (2-CysPrxs) are ubiquitous and highly abundant proteins that serve multiple functions as peroxidases, chaperones, and thiol oxidases and… Continue reading The conformational bases for the two functionalities of 2-cysteine peroxiredoxins as peroxidase and chaperone
2011 / Physical Chemistry Chemical Physics
Denaturant-induced conformational change of yeast iso-1-cytochrome c (Cytc) has been comprehensively investigated in the single-molecule and bulk phases. By fluorescence-quenching experiments with dye-labelled heme-protein (Alexa… Continue reading Unfolding dynamics of cytochrome c revealed by single-molecule and ensemble-averaged spectroscopy
2009 / Colloids and Surfaces B: Biointerfaces
A novel nanocomposite based on TiO2–protein for functional applications was prepared and characterized. The composite was made by covalent immobilisation… Continue reading Nanocomposite based on modified TiO2–BSA for functional applications
2008 / Cell Calcium
The peptide of HIV-1 envelope gp41 (a.a 628–683), referred to herein as P5, contains P1, a conserved galactose-specific lectin domain… Continue reading The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent
2003 / The Journal of Biological Chemistry
About one-third of the amino acid residues conserved in all scorpion long chain Na channel toxins are aromatic residues, some… Continue reading Importance of the Conserved Aromatic Residues in the Scorpion α-Like Toxin BmK M1 THE HYDROPHOBIC SURFACE REGION REVISITED
2002 / Biochemistry
Mammaglobin, a promising diagnostic marker for breast cancer, forms a covalent complex with lipophilin B. mRNA levels for each component… Continue reading Purification and Characterization of the Mammaglobin/Lipophilin B Complex, a Promising Diagnostic Marker for Breast Cancer
