Analysis of the pH-dependent thermodynamic stability, local motions, and microsecond folding kinetics of carbonmonoxycytochrome c

2016 / Archives of Biochemistry and Biophysics

This paper analyzes the effect of pH on thermodynamic stability, low-frequency local motions and microsecond folding kinetics of carbonmonoxycytochrome c (Cyt-CO) all… Continue reading Analysis of the pH-dependent thermodynamic stability, local motions, and microsecond folding kinetics of carbonmonoxycytochrome c

Leah Pandiscia, PhD

Tuning of Supramolecular Architectures of l-Valine-Containing Dicyanoplatinum(II) 2,2’-Bipyridine Complexes by Metal–Metal, p–p Stacking, and Hydrogen-Bonding Interactions

2016 / Chemistry A European Journal

A series of newly synthesized dicyanoplatinum(II) 2,2’-bipyridine complexes exhibits self-assembly properties in solution after the incorporation of the l-valine amino… Continue reading Tuning of Supramolecular Architectures of l-Valine-Containing Dicyanoplatinum(II) 2,2’-Bipyridine Complexes by Metal–Metal, p–p Stacking, and Hydrogen-Bonding Interactions

Leah Pandiscia, PhD

Point mutation (R153H or R153C) in Escherichia coliisocitrate dehydrogenase: Biochemical characterization and functional implication

2016 / Journal of Basic Microbiology

Arginine 132 (R132) mutations to histidine or cysteine frequently occur to cytosolic NADP+-isocitrate dehydrogenase (IDH1) in secondary glioblastoma multiforme (GBM)… Continue reading Point mutation (R153H or R153C) in Escherichia coliisocitrate dehydrogenase: Biochemical characterization and functional implication

Leah Pandiscia, PhD

High affinity binding of the receptor-associated protein D1D2 domains with the LDL receptor-related protein (LRP1) involves bivalent complex formation: Critical roles of lysine 60 and 191.

2016 / The Journal of Biological Chemistry

The LDL receptor-related protein 1 (LRP1) is a large endocytic receptor that binds and mediates the endocytosis of numerous structurally… Continue reading High affinity binding of the receptor-associated protein D1D2 domains with the LDL receptor-related protein (LRP1) involves bivalent complex formation: Critical roles of lysine 60 and 191.

Leah Pandiscia, PhD

N-terminal domain of PB1-F2 protein of influenza A virus can fold into amyloid-like oligomers and damage cholesterol and cardiolipid containing membranes

2016 / Biochemical and Biophysical Research Communications

PB1-F2 protein is a factor of virulence of influenza A viruses which increases the mortality and morbidity associated with infection.… Continue reading N-terminal domain of PB1-F2 protein of influenza A virus can fold into amyloid-like oligomers and damage cholesterol and cardiolipid containing membranes

Leah Pandiscia, PhD