RNase P is involved in processing the 5′ end of pre-tRNA molecules. Bacterial RNase P contains a catalytic RNA subunit… Continue reading Functional role of putative critical residues in Mycobacterium tuberculosis RNase P protein
Leah Pandiscia, PhD
July 28, 2017
Guanine-rich sequences are able to form quadruplexes consisting of G-quartet structural units. Quadruplexes play an important role in the regulation… Continue reading Sr2+ induces unusually stable d(GGGTGGGTGGGTGGG) quadruplex dimers
Leah Pandiscia, PhD
July 28, 2017
Hypoxia-inducible factor (HIF) is highly expressed in most of cancer cell. The Mn(II)-aptamer based nanoclusters with 3D structures would be… Continue reading Mn(II) silver-aptamer clusters for target MR image of tumor
Leah Pandiscia, PhD
July 28, 2017
Amyloid aggregation of α-synuclein (AS) is one of the hallmarks of Parkinson’s disease. The interaction of copper ions with the… Continue reading Role of N-terminal methionine residues in the redox activity of copper bound to alpha-synuclein
Leah Pandiscia, PhD
July 28, 2017
This paper analyzes the effect of pH on thermodynamic stability, low-frequency local motions and microsecond folding kinetics of carbonmonoxycytochrome c (Cyt-CO) all… Continue reading Analysis of the pH-dependent thermodynamic stability, local motions, and microsecond folding kinetics of carbonmonoxycytochrome c
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
May 24, 2018
Leah Pandiscia, PhD
July 28, 2017
Site-directed spin labeling of RNA based on click chemistry is used in combination with pulsed electron-electron double resonance (PELDOR) to… Continue reading Post-synthetic Spin-Labeling of RNA through Click Chemistry for PELDOR Measurements
Leah Pandiscia, PhD
July 28, 2017
EcoP15I DNA methyltransferase (M.EcoP15I) recognizes short asymmetric sequence, 5′-CAGCAG-3′, and methylates the second adenine only on one strand of the… Continue reading Asymmetric DNA methylation by dimeric EcoP15I DNA methyltransferase
Leah Pandiscia, PhD
July 28, 2017
yfdX proteins are ubiquitously present in a large number of virulent bacteria. A member of this family of protein in E.… Continue reading Reversible thermal unfolding of a yfdX protein with chaperone-like activity
Leah Pandiscia, PhD
July 28, 2017
Several polyaniline, PANI, nanofibers, with controlled morphology and chiroptical properties were fabricated by using two developed unusual interfacial syntheses, UIS.… Continue reading Controlling the morphology and chiroptical properties of polyaniline nanofibers by unusual interfacial synthesis
Leah Pandiscia, PhD
July 28, 2017
Peptide-conjugated nanoparticles (NPs) have promising potential for applications in biosensing, diagnosis, and therapeutics, due to their appropriate size, and unique… Continue reading Nanoparticle assembly and gelatin binding mediated by triple helical collagen mimetic peptide
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Arginine 132 (R132) mutations to histidine or cysteine frequently occur to cytosolic NADP+-isocitrate dehydrogenase (IDH1) in secondary glioblastoma multiforme (GBM)… Continue reading Point mutation (R153H or R153C) in Escherichia coliisocitrate dehydrogenase: Biochemical characterization and functional implication
Leah Pandiscia, PhD
July 28, 2017
The potassium channel Kv 1.3 plays a vital part in the activation of T lymphocytes and is an attractive pharmacological… Continue reading Mapping the Interaction Anatomy of BmP02 on Kv1.3 Channel
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Aureochrome (Aureo) is a recently discovered blue light sensor protein initially from Vaucheria frigida, in which it controls blue light-dependent branch… Continue reading Time-Resolved Detection of Light-Induced Dimerization of Monomeric Aureochrome-1 and Change in Affinity for DNA
Leah Pandiscia, PhD
July 28, 2017
Glycine oxidase (GO), a type of d-amino acid oxidase, is of biotechnological interest for its potential in several fields. In… Continue reading Asn336 is involved in the substrate affinity of glycine oxidase from Bacillus cereus
Leah Pandiscia, PhD
July 28, 2017
Serum albumin is the most abundant protein in the circulatory system to transport fatty acids, metabolites and drugs. In this… Continue reading Self-healing of thermally-induced, biocompatible and biodegradable protein hydrogel
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017