2015 / Chirality
A receptor assembly composed of iron(II) triflate and pyridine-2,6- dicarbaldehyde was used to determine the enantiomeric excess (ee) of alpha-chiral… Continue reading Chiral Amine Enantiomeric Excess Determination Using Self-Assembled Octahedral Fe(II)-Imine Complexes
2012 / Protein Expression and Purification
High amounts of membrane protein samples are needed for structural or functional analysis and a first bottleneck is often to… Continue reading A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems
2015 / Food Chemistry
Polygonatum odoratum is widely used as a traditional food supplement and herbal medicine with strong antioxidant activity. However, systematic investigation of… Continue reading Antioxidant homoisoflavonoids from Polygonatum odoratum
2015 / Biomaterials
KLD-12 (KLD) is a 12-residue self-assembling peptide that can adopt nano-structures and is known for its tissue-engineering properties. Our objective… Continue reading Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties
2013 / Journal of Colloid and Interface Science
Herein, a novel single-chain coumarin-substituted diacetylene monomer (CODA) was synthesized. CODA LB films exhibited obvious chirality although CODA monomer was… Continue reading Thermochromism and supramolecular chirality of the coumarin-substituted polydiacetylene LB films
2014 / Chemistry A European Journal
A new responsive material composed of an amphiphilic light-switchable dithienylethene unit functionalized with a hydrophobic cholesterol unit and a hydrophilic… Continue reading Light-Controlled Formation of Vesicles and Supramolecular Organogels by a Cholesterol-Bearing Amphiphilic Molecular Switch
2014 / Acta Biomaterialia
Defects in the corneal stroma caused by trauma or diseases such as macular corneal dystrophy and keratoconus can be detrimental… Continue reading Bioactive self-assembled peptide nanofibers for corneal stroma regeneration
2013 / Polymer
A simple water-soluble pyrene-functionalized cationic polyelectrolyte poly(4- vinylpyridine) quaternary ammonium (P4VP-Py-Bu) was designed and synthesized from poly(4-vinylpyridine) by two-step quaternization… Continue reading Synthesis and fluorescence study of a pyrene-functionalized poly(4-vinylpyridine) quaternary ammonium for detection of DNA hybridization
2014 / FEBS Open Bio
Structure-switching molecules provide a unique means for analyte detection, generating a response to analyte concentration through a binding-specific conformational change… Continue reading Rational design of a structure-switching DNA aptamer for potassium ions
2012 / Molecular Nutrition & Food Research
The aims of this study were to evaluate IgE-mediated hypersensitivity to pine nut with details of clinical reactions and to… Continue reading Pine nut allergy: Clinical features and major allergens characterization
2014 / RSC Advances
A broad spectrum of peptides and proteins can self assemble to form amyloid or amyloid like fibrils under appropriate conditions.… Continue reading Zn2+, Cd2+ and Cu2+ mediated formation of amyloid like fibrils by the monomers of β-sheet rich peanut agglutinin
2012 / nature
Self-assembly provides an attractive route to functional organic materials, with properties and hence performance depending sensitively on the organization of… Continue reading Pathway complexity in supramolecular polymerization
2015 / International Journal of Biological Macromolecules
An amylase of a thermophilic bacterium, Bacillus sp. TSSC-3 (GenBank Number, EU710557) isolated from the Tulsi Shyam hot spring reservoir (Gujarat, India) was… Continue reading Enzyme stability, thermodynamics and secondary structures of α-amylase as probed by the CD spectroscopy
2013 / The Journal of Biological Chemistry
Talin activates integrins, couples them to F-actin, and recruits vinculin to focal adhesions (FAs). Here, we report the structural characterization… Continue reading RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover*
2013 / Analytical Biochemistry
The eukaryotic initiation factor 4E (eIF4E) is the key component of the translational initiation complex that recruits mRNA by binding… Continue reading Solution-based approach to study binding to the eIF4E cap-binding site using CD spectroscopy
2013 / Science China Technological Sciences
Four achiral Cu(II)-coordinated Schiff bases complexes containing aromatic structures were synthesized and their supramolecular assemblies at the air/water interface were… Continue reading Interfacial assembly of a series of Cu(II)-coordinated Schiff bases complexes: orderly nanostructures and supramolecular chirality
2015 / Chemical Science
Although the importance of circularly polarized luminescence (CPL) materials has been widely recognized, the CPL responses of supramolecular gels are… Continue reading Strong Circularly Polarized Luminescence from the Supramolecular Gels of an Achiral Gelator: Tunable Intensity and Handedness
2013 / The Journal of Biological Chemistry
Domain V of the 23S/25S/28S rRNA of the large ribosomal subunit constitutes the active center for the protein folding activity… Continue reading The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition
2015 / Physical Chemistry Chemical Physics
It is shown that the antiprotozoal drugs berenil and pentamidine, conventional minor groove binders of DNA, form non-covalent complexes with… Continue reading Glycosaminoglycans are potential pharmacological targets for classic DNA minor groove binder drugs berenil and pentamidine
2014 / Analytical and Bioanalytical Chemistry
The FDA has approved more than 100 protein and peptide drugs with hundreds more in the pipeline (Lanthier et al.… Continue reading Analytical techniques and bioactivity assays to compare the structure and function of filgrastim (granulocyte-colony stimulating factor) therapeutics from different manufacturers
