2008 / Chirality
To obtain accurate and consistent measurements from circular dichroism (CD) instruments over time and from different laboratories, it is important… Continue reading A new reference material for UV–visible circular dichroism spectroscopy
2011 / Biophysics Letters
The biological activity of therapeutic proteins is strongly dependent on the stability of their folded state, which can easily be… Continue reading FTIR markers of methionine oxidation for early detection of oxidized protein therapeutics
1999 / JACS
Synthetic protocols and circular dichroism (CD) spectra are reported for a series of oligomers of (R,R)-trans-2-aminocyclopentanecarboxylic acid (trans-ACPC). The two… Continue reading Synthesis and Structural Characterization of Helix-Forming â-Peptides: trans-2-Aminocyclopentanecarboxylic Acid Oligomers
2013 / Molecules
Solvent chirality transfer of (S)-/(R)-limonenes allows the instant generation of optically active PF8P2 aggregates with distinct circular dichroism (CD)/circularly polarized luminescence (CPL)… Continue reading Mirror-Symmetry-Breaking in Poly[(9,9-di-n-octylfluorenyl- 2,7-diyl)-alt-biphenyl] (PF8P2) is Susceptible to Terpene Chirality, Achiral Solvents, and Mechanical Stirring
2011 / Chemistry A European Journal
Monobenzylated sugar amino acids (SAAs) that differ in ether ring size (containing an oxetane, furanoid, and pyranoid ring) were synthesized… Continue reading Exploring the Conformational and Biological Versatility of β-Turn-Modified Gramicidin S by Using Sugar Amino Acid Homologues that Vary in Ring Size
2005 / Chirality
A series of sugar amino acids, based on open chain sugars, have been oligomerised and cyclised. The resulting cyclic carbopeptoids… Continue reading Circular dichroism studies of carbopeptoid-cyclodextrins
2008 / Chirality
Sugar amino acids and their oligomers, known as carbopeptoids, are commonly studied as foldamers. However, study of their conformational preference… Continue reading Spectroscopic studies of oligomers containing 2,5-trans furanoid sugar amino acids
2014 / Journal of Analytical Methods in Chemistry
Protein structure depends on weak interactions and covalent bonds, like disulfide bridges, established according to the environmental conditions. Here, we… Continue reading Comparability of a Three-Dimensional Structure in Biopharmaceuticals Using Spectroscopic Methods
2016 / International Journal of Molecular Sciences
Glucose-6-phosphate dehydrogenase (G6PD) deficiency in humans causes severe disease, varying from mostly asymptomatic individuals to patients showing neonatal jaundice, acute… Continue reading Functional and Biochemical Characterization of Three Recombinant Human Glucose-6-Phosphate Dehydrogenase Mutants: Zacatecas, Vanua-Lava and Viangchan
2016 / Sustainable Chemistry & Engineering
A vortex fluidic device (VFD) is effective for downstream processing of C-phycocyanin (C-PC) from blue-green microalga Spirulina maxima using an aqueous two… Continue reading Vortex Fluidic Device-Intensified Aqueous Two Phase Extraction of C-Phycocyanin from Spirulina maxima
2016 / ChemMedChem
1,10-Phenanthroline (Phen) derivatives are attractive ligands to provide metal complexes that are selective for different DNA secondary structures. Herein, we… Continue reading Molecular Basis for Differential Recognition of G-Quadruplex versus Double-Helix DNA by Bis-Phenanthroline Metal Complexes
2016 / Molecular and Cellular Biology
HDM2 and HDMX are key negative regulatory factors of the p53 tumour suppressor under normal conditions by promoting its degradation… Continue reading Allosteric interactions by p53 mRNA governs HDM2 E3 ubiquitin ligase specificity under different conditions
2016 / The Journal of Cell Biology
Basement membranes are defining features of the cellular microenvironment; however, little is known regarding their assembly outside cells. We report… Continue reading Extracellular chloride signals collagen IV network assembly during basement membrane formation
2016 / Nature Communications
In natural habitats, plants frequently experience rapid changes in the intensity of sunlight. To cope with these changes and maximize… Continue reading A voltage-dependent chloride channel fine-tunes photosynthesis in plants
2016 / Journal of Molecular Liquids
Herein, we have reported the study of interaction of model protein, bovine serum albumin (BSA), and a sipholane triterpenoid, named… Continue reading Biophysical characterization of the interaction of bovine serum albumin with anticancer sipholane triterpenoid from the Red Sea sponge
2016 / Dalton Transactions
Copper complexes formed by an amino terminal Cu2+- and Ni2+-binding (ATCUN) motif have attracted attention as metallodrug candidates that cleave… Continue reading Enhanced stability of Cu2+–ATCUN complexes under physiologically relevant conditions by insertion of structurally bulky and hydrophobic amino acid residues into the ATCUN motif
2016 / Proteins: Structure, Function, and Bioinformatics
The amyloid β-peptide fragment comprising residues 25-35 (Aβ25-35) is known to be the most toxic fragment of the full length… Continue reading Hydrophobic tail length plays a pivotal role in amyloid beta (25-35) fibril-surfactant interactions
2016 / Applied Materials and Interfaces
In this study, an artificial hydrolase was developed by combining the catalytic Ser/His/Asp triad with N-fluorenylmethoxycarbonyl diphenylalanine (Fmoc-FF), followed by coassembly… Continue reading Enhancing the Activity of Peptide-Based Artificial Hydrolase with Catalytic Ser/His/Asp Triad and Molecular Imprinting
2016 / Biotechnological Products and Process Engineering
The biotransformation of tanshinone IIA to a new antibacterial agent tanshisorbicin (1) by the fungusHypocrea sp. (AS 3.17108) is described. The… Continue reading Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity
2016 / Food Hydrocolloids
Bovine α-lactalbumin (ALA) is an important Ca-binding protein of milk. Epigallocatechin-3-gallate (EGCG) is the major and the most biologically active… Continue reading Noncovalent interactions of bovine α-lactalbumin with green tea polyphenol, epigalocatechin-3-gallate
