2020 / New Journal of Chemistry
The implication of G4 DNA in biologically important roles has prompted the search for selective recognition and interaction of G4… Continue reading An Amphiphilic BODIPY： Selective Probe for Parallel G4 DNA Targeting via Disaggregation-Induced Emission
2020 / International Journal of Biological Macromolecules
In dimeric near-infrared (NIR) biomarkers engineered from bacterial phytochromes the covalent binding of BV to the cysteine residue in one… Continue reading Probing the allostery in dimeric near-infrared biomarkers derived from the bacterial phytochromes: The impact of the T204A substitution on the inter-monomer interaction
2020 / Toxicon: X
A bioactive compound isolated from the stem extract of Aristolochia sprucei through High Performance Liquid Chromatography (HPLC) was identified via Nuclear Magnetic… Continue reading Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity
2020 / Journal of Peptide Science
Previously, we described the design and synthesis of three nine‐residue AMPs, P9Nal(SS), P9Trp(SS), and P9Nal(SR), showing high stability in serum… Continue reading Similarities and differences for membranotropic action of three unnatural antimicrobial peptides
2020 / Phytochemistry
Three undescribed spirosteroids, asparacemosones A–C, an undescribed spiro-21-norsteroid, asparacemosone D, along with seven known compounds were isolated from Thai herbal… Continue reading Spirosteroids and α-glucosidase inhibitory norlignans from Asparagus racemosus Willd. roots
2020 / Food Chemistry
Ara h1 is a major allergen from peanut. We investigated the effect of covalent conjugation of Ara h1 and dietary… Continue reading Covalent conjugation with (−)-epigallo-catechin 3-gallate and chlorogenic acid changes allergenicity and functional properties of Ara h1 from peanut
2020 / Materials Advances
Different small molecules and nanomaterials have been known as inhibitors of protein misfolding and subsequent fibrillation, which marks the initiation… Continue reading Polyphenol capping on gold nanosurface modulates human serum albumin fibrillation
2020 / Fitoterapia
Two new tetrahydrofuran derivatives named aspericacids A and B (1 and 2) were isolated from the metabolites produced by the sponge-associated Aspergillus sp. LS78.… Continue reading New antifungal tetrahydrofuran derivatives from a marine sponge-associated fungus Aspergillus sp. LS78
2020 / Journal of Biological Chemistry
The transcription factor iron response regulator (Irr) is a key regulator of iron homeostasis in the nitrogen-fixating bacterium Bradyrhizobium japonicum.… Continue reading Mechanistic insights into heme-mediated transcriptional regulation via a bacterial manganese-binding iron regulator, iron response regulator (Irr)
2020 / Carbohydrate Polymers
Amylose, as a linear biopolymer, tends to form helical inclusion complexes with suitable guest species. This is of great importance… Continue reading Preparation of amylose-poly(methyl methacrylate) inclusion complex as a smart nanocarrier with switchable surface hydrophilicity
2020 / Nature Communications
The close synergy between peptides and nucleic acids in current biology is suggestive of a functional co-evolution between the two… Continue reading Mutually stabilizing interactions between proto-peptides and RNA
2020 / Nucleic Acids Research
Z-DNA is known to be a left-handed alternative form of DNA and has important biological roles as well as being… Continue reading Oligonucleotides DNA containing 8-trifluoromethyl-2′-deoxyguanosine for observing Z-DNA structure
2020 / Colloids and Surfaces B: Biointerfaces
In this study using phospholipids with high transition temperature and taking advantage of PEGylation, we designed liposomal formulation targeted with… Continue reading Folate targeted PEGylated liposomes for the oral delivery of insulin: In vitro and in vivo studies
2020 / Macromolecular Bioscience
Gliadin, a component of gluten and a known epitope, is implicated in celiac disease (CeD) and results in an inflammatory… Continue reading Aqueous RAFT Synthesis of Low Molecular Weight Anionic Polymers for Determination of Structure/Binding Interactions with Gliadin
2020 / Biochimie
The evolution of Staphylococcus aureus (S. aureus) with the ability to acquire and develop resistance to antibiotics has been described as a distinct… Continue reading CPF-C1 analog with effective antimicrobial and antibiofilm activities against Staphylococcus aureus including MRSA
2020 / Journal of Biological Chemistry
In humans, mutations in genes encoding homologs of the DNA mismatch repair endonuclease MutL cause a hereditary cancer that is… Continue reading A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL
2020 / European Journal of Medicinal Chemistry
Natural cardiac-active principles built upon the 14,16β-dihydroxy-5β,14β-androstane core and bearing a heterocyclic substituent at 17β, in particular, a cardenolide –… Continue reading Synthesis and evaluation of Na+/K+-ATP-ase inhibiting and cytotoxic in vitro activities of oleandrigenin and its selected 17β-(butenolidyl)- and 17β-(3-furyl)- analogues
2020 / Enzyme and Microbial Technology
We report, for the first time, the three-dimensional structure and biochemical properties of a UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase (GalE-like L-ThrDH) from Phytophthora… Continue reading Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans
2020 / Steriods
Two novel steroidal derivatives, erectsterates A (1) and B (2), a pair of epimers at C-10, were isolated from the… Continue reading Erectsterates A and B, a pair of novel highly degraded steroid derivatives from the South China Sea soft coral Sinularia erecta
2020 / ChemPlusChem
A heating treatment method for the synthesis of fluorescent nanoparticles using simple N‐(9‐fluorenylmethoxycarbonyl) (Fmoc)‐protected tripeptides is reported. Two pairs of… Continue reading Thermally Induced Structural Transition of Peptide Nanofibers into Nanoparticles with Enhanced Fluorescence Properties
