2016 / Biochemical and Biophysical Research Communications
Vertebrate lens is one of the tissues with the highest soluble protein concentration. The predominant soluble proteins in lens fiber… Continue reading Membrane insertion of αA-crystallin is oligomer-size dependent
2016 / Biochimica et Biophysica Acta-Biomembranes
The short membrane-active peptide BP100 [KKLFKKILKYL-NH2] is known as an effective antimicrobial and cell penetrating agent. For a functional alanine… Continue reading Alanine scan and 2H-NMR analysis of the membrane-active peptide BP100 points to a distinct carpet mechanism of action
2016 / Journal of Inorganic Biochemistry
A number of biological functions have been ascribed to mammalian metallothioneins (MTs) including zinc and copper homeostatic regulation, redox activity… Continue reading Cadmium binding mechanisms of isolated domains of human MT isoform 1a: Non-cooperative terminal sites and cooperative cluster sites
2016 / Journal of Structural Biology
Thanatos associated protein 11 (THAP11) is a cell cycle and cell growth regulator differentially expressed in cancer cells. THAP11 belongs… Continue reading The C-terminal region of the transcriptional regulator THAP11 forms a parallel coiled-coil domain involved in protein dimerization
2016 / Biomaterials
By its unique advantages over traditional medicine, nanomedicine has offered new strategies for cancer treatment. In particular, the development of… Continue reading Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance
2016 / International Journal of Pharmaceutics
The aim of this work was to use annealing as a tool to optimize the lyophilization cycle by decreasing its… Continue reading Annealing as a tool for the optimization of lyophilization and ensuring of the stability of protein-loaded PLGA nanoparticles
2016 / New Journal of Chemistry
Surfactant interaction can influence the protein structure manifesting molecular unfolding–folding. The interaction can also affect the self-assembly formation of the… Continue reading Detailed characterization of Lysozyme (Lyz)-surfactant (SDDS) interaction, and the structural transitions
2016 / Science Advances
Circular dichroism and optical rotation are crucial for the characterization of chiral molecules and are of importance to the study… Continue reading Resolving enantiomers using the optical angular momentum of twisted light
2016 / Intrinsically Disordered Protein
Curli are a type of proteinaceous cell surface filament produced by enteric bacteria such as Escherichia and Salmonella that facilitate cell adhesion and invasion,… Continue reading Are the Curli Proteins CsgE and CsgF Intrinsically Disordered ?
2016 / Chemical Science
We report the crystallization of homochiral polyoxometalate (POM) macroanions {CoSb6O4(H2O)3[Co(hmta)SbW8O31]3}15− (1, hmta = hexamethylenetetramine) via the counter cation-mediated chiral symmetry breaking and asymmetric… Continue reading Cation-mediated optical resolution and anticancer activity of chiral polyoxometalates built from entirely achiral building blocks
2016 / International Journal of Molecular Sciences
The early cysteine-labeled metallothionein (MT) from Triticum aestivum (common wheat), denoted Ec-1, features two structurally well-defined domains, γ and βE, coordinating two… Continue reading Localization and Spectroscopic Analysis of the Cu(I) Binding Site in Wheat Metallothionein Ec-1
2016 / Organic and Biomolecular Chemistry
The stabilization of G-quadruplex DNA structures by using small molecule ligands having simple structural scaffolds has the potential to be… Continue reading Benzothiazole hydrazone of furylbenzamides preferentially stabilize c-MYC and c-KIT1 promoter G-quadruplex DNAs
2016 / RSC Advances
Andrographolide sodium bisulphite (ASB) injection was widely used in China for the treatment of infectious diseases. The chemical analysis of ASB injection… Continue reading Isolation and characterization of related impurities in andrographolide sodium bisulphite injection†
2016 / PLoS ONE
Type 2 asparaginases, a subfamily of N-terminal nucleophile (Ntn) hydrolases, are activated by limited proteolysis. This activation yields a heterodimer… Continue reading Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1
2016 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Four different transition metal complexes containing dipyridyl triazole ligands, namely [Cu(abpt)2Cl2]·2H2O (1), [Cu(abpt)2(ClO4)2] (2), [Co2(abpt)2(H2O)2Cl2]·Cl2·4H2O (3) and [Co2(Hbpt)2(CH3OH)2(NO3)2] (4) have… Continue reading Synthesis, characterization, DNA/protein interaction and cytotoxicity studies of Cu(II) and Co(II) complexes derived from dipyridyl triazole ligands
2016 / Journal of Luminescence
Two asymmetric monocationic trimethine cyanine dyes were obtained via condensation reaction between 2-methylbenzothialolium salts containing various (aliphatic and benzyl) substituents… Continue reading Novel synthetic approach to asymmetric monocationic trimethine cyanine dyes derived from N-ethyl quinolinum moiety. Combined fluorescent and ICD probes for AT-DNA labelling
2016 / Journal of Photochemistry and Photobiology B: Biology
The functionality of a gene carrying nucleic acid in an artificial gene-delivery system is important for the overall efficiency of… Continue reading Molecular recognition of genomic DNA in a condensate with a model surfactant for potential gene-delivery applications
2016 / Bioresource Technology
This study has assessed four invasive weeds, viz. Saccharum spontaneum (SS),Mikania micrantha (MM), Lantana camara (LC) and Eichhornia crassipes (EC) for enzymatic hydrolysis prior to bioalcohol fermentation.… Continue reading Mechanistic investigation in ultrasound induced enhancement of enzymatic hydrolysis of invasive biomass species
2016 / Structure
Lys48-linked ubiquitin chains act as the main targeting signals for protein degradation by the proteasome. Here we report selective binding… Continue reading Selective Binding of AIRAPL Tandem UIMs to Lys48-Linked Tri-Ubiquitin Chains
2016 / Colloids and Surfaces B: Biointerfaces
Here we showed that gliadin, a complex protein system related to celiac disease and other human diseases, is spontaneously self-organized… Continue reading Self-organization of gliadin in aqueous media under physiological digestive pHs
