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Synthesis, characterization, and antitumor activity of three ternary dinuclear copper (II) complexes with a reduced Schiff base ligand and diimine coligands in vitro and in vivo

2016 / Journal of Inorganic Biochemistry

Three ternary copper (II) complexes containing 1,10-phenanthroline (phen, 1), dipyrido[3,2-d:2′,3′-f]quinoxaline (dpq, 2) and dipyrido[3,2-a:2′,3′-c]phenazine (dppz, 3), with the formulation [Cu2(NCL)2(H4PASP)]·4.5H2O (1–3) (where NCL = the… Continue reading Synthesis, characterization, and antitumor activity of three ternary dinuclear copper (II) complexes with a reduced Schiff base ligand and diimine coligands in vitro and in vivo

Leah Pandiscia, PhD July 28, 2017

Arginine-Rich Ionic Complementary Peptides as Potential Drug Carriers: Impact of Peptide Sequence on Size, Shape and Cell Specificity

2016 / Nanomedicine: Nanotechnology, Biology, and Medicine

Ionic complementary peptides have shown potential in delivering hydrophobic anticancer drugs. In this study, a series of four ionic complementary… Continue reading Arginine-Rich Ionic Complementary Peptides as Potential Drug Carriers: Impact of Peptide Sequence on Size, Shape and Cell Specificity

Leah Pandiscia, PhD July 28, 2017

Synthesis, electrochemical, spectral and DFT study of novel thiazole-annelated subphthalocyanines with inherent chirality

2016 / Dyes and Pigments

Five-membered thiazole-annelated subphthalocyanine derivatives have been prepared for the first time. Both regioisomers with C3 and C1 molecular symmetry have been isolated and optical… Continue reading Synthesis, electrochemical, spectral and DFT study of novel thiazole-annelated subphthalocyanines with inherent chirality

Leah Pandiscia, PhD July 28, 2017

A dinuclear copper(II) complex with piperazine bridge ligand as a potential anticancer agent: DFT computation and biological evaluation

2016 / Inorganica Chimica Acta

New dinuclear complex [Cu2(bpy)2(im)2(pip)(NO3)2]·2NO3, 1 was synthesized and characterized by elemental analysis and various spectroscopic methods (IR, 1H and 13C NMR, EPR, UV–Vis, ESI–MS… Continue reading A dinuclear copper(II) complex with piperazine bridge ligand as a potential anticancer agent: DFT computation and biological evaluation

Leah Pandiscia, PhD July 28, 2017

Dissecting the structural and functional features of the Luteinizing hormone receptor using receptor specific single chain fragment variables

2016 / Molecular and Cellular Endocrinology

The Luteinizing hormone receptor (LHR) has a large extracellular domain (amino acid residues, a.a.1–355) and a transmembrane domain (TMD; a.a.… Continue reading Dissecting the structural and functional features of the Luteinizing hormone receptor using receptor specific single chain fragment variables

Leah Pandiscia, PhD July 28, 2017

A new polyketide synthase−nonribosomal peptide synthetase hybrid metabolite from plant endophytic fungus Periconia sp.

2016 / Chinese Chemical Letters

A new polyketide synthase–nonribosomal peptide synthetase (PKS–NRPS) hybrid metabolite, named pericoannosin B (1), was isolated from endophytic fungus Periconiasp. F-31 of… Continue reading A new polyketide synthase−nonribosomal peptide synthetase hybrid metabolite from plant endophytic fungus Periconia sp.

Leah Pandiscia, PhD July 28, 2017