Triple helical nucleic acids or triplex are formed from the combination of three oligonucleotides. In the double stranded form the… Continue reading An overview on the interaction of phenazinium dye phenosafranine to RNA triple and double helices
Leah Pandiscia, PhD
July 28, 2017
In this study, a colorimetric method was exploited to detect bisphenol A (BPA) based on BPA-specific aptamer and cationic polymer-induced… Continue reading Colorimetric detection of bisphenol A based on unmodified aptamer and cationic polymer aggregated gold nanoparticles
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A new circular dichroism sensor for detecting Ni2+ and Co2+ was proposed for the first time using chiral chelating quantum dots. The… Continue reading A circular dichroism sensor for Ni2+ and Co2+ based on L-cysteine capped cadmium sulfide quantum dots
Leah Pandiscia, PhD
July 28, 2017
Four novel pregnane-NSAIDs prodrugs 3β-(2-(6-methoxynaphthalene-2yl) propionoxy)-16α-methoxy-pregn-5-ene-20-one (3), 16α-methoxy-pregn-5-ene-20-one-3yl-2(4-iso butyl phenyl) propanoate (4), 3β-(2-(6-methoxynaphthalene-2yl) propionoxy) 20-hydroxy-16α-methoxy-pregn-5-ene (5) and 20-hydroxy-16α-methoxy-pregn-5-ene-20-one-3yl-2(4-iso butyl phenyl)… Continue reading Expedient synthesis of novel pregnane-NSAIDs prodrugs, XRD, stereochemistry of their C-20 derivatives by circular dichroism, conformational analysis, their DFT and TD-DFT studies
Leah Pandiscia, PhD
July 28, 2017
It is shown that in water with no added salts calf-thymus DNA and its drug-loaded forms exhibit peculiar, completely reversible… Continue reading Apparent circular dichroism signature of stirring-oriented DNA and drug–DNA complexes
Leah Pandiscia, PhD
July 28, 2017
The octahedral cobalt(III) complexes with (S,S)-ethylenediamine-N,N′-di-2-propionic (S,S-eddp) and (S,S)-ethylenediamine-N,N′-di-2-(3-methyl)-butanoic (S,S-eddv) acids and oxalato and malonato ligands, as additional bidentate ligands,… Continue reading Stereospecific ligands and their complexes. Part XXI. Synthesis, characterization, circular dichroism and antimicrobial activity of cobalt(III) complexes with some edda-type of ligands. Crystal structure of potassium-Δ-(−)589-s-cis-oxalato-(S,S)-ethylenediamine-N,N′-di-(2-propanoato)-cobaltate(III)-semihydrate, K-Δ-(−)589-s-cis-[Co(S,S-eddp)(ox)]·0.5H2O
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Five new chiral dioxidovanadium Schiff base complexes derived from l-valine, l-leucine,l-histidine, l-threonine and d-threonine were synthesized and characterized by elemental analysis, 1H and 51V NMR and… Continue reading X-ray structure analysis, electronic and vibrational circular dichroism of chiral-at-metal dioxidovanadium(V) complexes with amino acids derived Schiff base ligands
Leah Pandiscia, PhD
July 28, 2017
A series of novel tocainide analogues were characterized for their HSA and RSA binding, by using high-performance liquid affinity chromatography… Continue reading Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Thermostable lipases offer major biotechnological advantages over mesophilic lipases. In this study, an intracellular thermostable and organic solvent-tolerant lipase-producing strain… Continue reading A novel thermostable and organic solvent-tolerant lipase fromXanthomonas oryzae pv. oryzae YB103: screening, purification and characterization
Leah Pandiscia, PhD
July 28, 2017
Phytochemical investigation of the bark of Juglans sinensis Dode (Juglandaceae) led to the isolation of two active compounds, 8-hydroxy-2-methoxy-1,4-naphthoquinone (1) and 5-hydroxy-2-methoxy-1,4-naphthoquinone… Continue reading Cytotoxic Compounds from Juglans sinensis Dode Display Anti-Proliferative Activity by Inducing Apoptosis in Human Cancer Cells
Leah Pandiscia, PhD
July 28, 2017
A polysaccharide (MP21) was extracted and purified from Lepidium meyenii Walp. using DEAE-52 and Sephacryl™ S-500 columns. Its physicochemical properties and macrophage… Continue reading Immunomodulatory effects of a polysaccharide purified fromLepidium meyenii Walp. on macrophages
Leah Pandiscia, PhD
July 28, 2017
The histopathological hallmark of Alzheimer’s disease (AD) is the aggregation and accumulation of the amyloid beta peptide (Aβ) into misfolded… Continue reading A2T and A2V Aβ Peptides Exhibit Different Aggregation Kinetics, Primary Nucleation, Morphology, Structure and LTP Inhibition
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017