2016 / Talanta
Clinically, the amount of uric acid (UA) in biological fluids is closely related to some diseases such as hyperuricemia and… Continue reading Label-free and selective sensing of uric acid with gold nanoclusters as optical probe
2016 / International Journal of Biological Macromolecules
The influence of metal cations on G-quadruplex structure and peroxidase-mimicking DNAzyme activity was investigated. Experiments revealed a significant role of… Continue reading Hemin/G-quadruplex structure and activity alteration induced by magnesium cations
2016 / Archives of Biochemistry and Biophysics
Aggregation of globular proteins is an intractable problem which generally originates from partially folded structures. The partially folded structures first… Continue reading Physical basis for the ofloxacin-induced acceleration of lysozyme aggregation and polymorphism in amyloid fibrils
2016 / Journal of Materials Chemistry B
The present paper describes the fabrication of nanovesicles using the stirring induced self-assembly of a β-alanine homotetramer (H2N–βAla–βAla–βAla–βAla–CONH2) in an… Continue reading Self-assembly of β-alanine homotetramer: formation of nanovesicles for drug delivery
2016 / Journal of Peptide Science
The structure of peptide antibiotic gramicidin A (gA) was studied in phosphatidylcholin liposomes modified by nonionic detergent Triton X-100. First,… Continue reading Effective lipid-detergent system for study of membrane active peptides in fluid liposomes
2013 / Journal of Natural Products
In this study, the isolation, the structural characterization, and the elucidation of the biosynthetic origin of heterobactins, catecholate-hydroxamate mixed-type siderophores… Continue reading Structural Characterization of the Heterobactin Siderophores from Rhodococcus erythropolis PR4 and Elucidation of their Biosynthetic Machinery.
2016 / International Journal of Biological Macromolecules
The binding mode of a conformationally locked single bondNC(O)Nsingle bond planar system with deoxyribonucleic acid (DNA) is investigated using various spectroscopic and… Continue reading Alteration in DNA binding pattern of conformationally locked NC(O)N system: A spectroscopic investigation
2016 / RSC Advances
Bisphenols (BPs) are a group of chemicals with two hydroxyphenyl functionalities. BPs analogues including bisphenol A (BPA), bisphenol B (BPB),… Continue reading Bisphenol analogues differently affect human islet polypeptide amyloid formation
2016 / Journal of Biomolecular Structure and Dynamics
Kallikrein, a physiologically vital serine protease, was investigated for its functional and conformational transitions during chemical (organic solvents, Gdn-HCl), thermal,… Continue reading Functional Stability and Structural Transitions of Kallikrein: Spectroscopic and Molecular dynamics studies
2016 / Journal of Photochemistry and Photobiology A: Chemistry
6A,6X-Dideoxy-6A,6X-diamino-γ-cyclodextrins (X = B, C, D and E) 5a–d were synthesized as chiral hosts for catalyzing the enantiodifferentiating [4 + 4] photocyclodimerization of 2-anthracenecarboxylic acid (ACA).… Continue reading Enantiodifferentiating [4 + 4] photocyclodimerization of 2-anthracenecarboxylate catalyzed by 6A,6X-diamino-6A,6X-dideoxy-γ-cyclodextrins: Manipulation of product chirality by electrostatic interaction, temperature and solvent in supramolecular photochirogenesis
2016 / Marine Drugs
Chemical investigation of the cultures of marine Streptomyces sp. 182SMLY led to the discovery of two new polycyclic anthraquinones, which were elucidated… Continue reading Bioactive Polycyclic Quinones from Marine Streptomyces sp. 182SMLY
2016 / Talanta
Fluorescence anisotropy, known as a simple, homogeneous and cost-effective analytical technology, is an invaluable technique for studying the micro-environmental changes… Continue reading Modulating fluorescence anisotropy of dye-labeled DNA without involving mass amplification
2016 / Molecular Neurodegeneration
11Lrrk2, a gene linked to Parkinson’s disease, encodes a large scaffolding protein with kinase and GTPase activities implicated in vesicle… Continue reading LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate
2016 / Journal of Materials Chemistry C
Assemblies with helical fiber nanostructures were fabricated via simple ionic linkage of a cationic tetraphenylethylene derivative (TPEHexN+) and an anionic binaphthyl derivative… Continue reading The fabrication of helical fibers with circularly polarized luminescence viaionic linkage of binaphthol and tetraphenylethylene derivatives
2015 / Biochemistry
The conformational transition of the core domain of HIV-1 gp41 from a prehairpin intermediate to a six-helix bundle is responsible… Continue reading The C34 Peptide Fusion Inhibitor Binds to the Six-Helix Bundle Core Domain of HIV‑1 gp41 by Displacement of the C‑Terminal Helical Repeat Region
2015 / Inorganic Chemistry
Two new heterotrinuclear Fe–Ru–Fe complexes of ruthenium(II) tetraphenylporphyrin axially coordinated with a pair of isocyanoferrocene ((FcNC)2RuTPP, 1) or 1,1′-diisocyanoferrocene (([C5H4NC]2Fe)2RuTPP, 2) ligands… Continue reading Probing Electronic Communications in Heterotrinuclear Fe−Ru−Fe Molecular Wires Formed by Ruthenium(II) Tetraphenylporphyrin and Isocyanoferrocene or 1,1′-Diisocyanoferrocene Ligands
1997 / PNAS
An ultrarapid-mixing continuous-flow method has been developed to study submillisecond folding of chemically denatured proteins. Turbulent flow created by pumping… Continue reading Submillisecond protein folding kinetics studied by ultrarapid mixing
2016 / Phytochemistry Letters
Two new neo-lignans, erythro-7E-4′,9′-dihydroxy-4,5′-dimethoxy-5,8′-oxyneolign-7-en-9-al (1) and 4,5′-dimethoxy-lariciresinol (2) together with five known compounds (3-7) were isolated from the EtOAc-soluble extract of Eleutherococcus… Continue reading Inhibition effect of neo-lignans from Eleutherococcus senticosus (Rupt. & Maxim.) Maxim on diacylglycerol acyltransferase (DGAT)
2016 / International Journal of Biologocial Macromolecules
Recent studies have characterized the effects of aqueous ionic liquids on myoglobin unfolding for the broader purposes of understanding their… Continue reading Kinetics and mass spectrometric measurements of myoglobin unfolding in aqueous ionic liquid solutions
2016 / JACS
The fine control of enzyme activity is essential for the regulation of many important cellular and organismal functions. The light-regulation… Continue reading Small-Molecule-Triggered and Light-Controlled Reversible Regulation of Enzymatic Activity
